NACAD | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte	7 studies	19% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of NACAD at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	5030.82	2641 / 2642	100%	52.04	703 / 705
ovary	100%	1618.09	180 / 180	65%	6.26	279 / 430
prostate	91%	867.94	223 / 245	39%	1.92	194 / 502
uterus	98%	1652.49	167 / 170	29%	3.70	133 / 459
bladder	86%	945.10	18 / 21	17%	1.37	84 / 504
blood vessel	98%	1373.05	1311 / 1335	0%	0	0 / 0
breast	76%	560.93	349 / 459	22%	1.23	241 / 1118
esophagus	64%	964.30	929 / 1445	28%	2.10	52 / 183
adrenal gland	17%	182.73	44 / 258	70%	49.17	161 / 230
kidney	40%	222.33	36 / 89	46%	3.57	410 / 901
intestine	75%	1062.22	720 / 966	9%	0.62	48 / 527
lung	58%	352.30	338 / 578	22%	1.58	258 / 1155
adipose	73%	532.95	880 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	69%	4.96	55 / 80
heart	66%	450.48	565 / 861	0%	0	0 / 0
stomach	48%	532.59	171 / 359	14%	1.03	41 / 286
pancreas	0%	0	0 / 328	58%	5.64	104 / 178
skin	19%	99.32	341 / 1809	38%	3.59	181 / 472
thymus	14%	80.57	94 / 653	27%	1.79	166 / 605
spleen	23%	129.99	56 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	7%	0.42	3 / 45
liver	0%	0	0 / 226	2%	0.09	9 / 406
muscle	1%	6.73	11 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0015031	Biological process	protein transport
GO_0006612	Biological process	protein targeting to membrane
GO_0005737	Cellular component	cytoplasm
GO_0005854	Cellular component	nascent polypeptide-associated complex
GO_0005634	Cellular component	nucleus
GO_0051082	Molecular function	unfolded protein binding
GO_0005515	Molecular function	protein binding

Gene name	NACAD
Protein name	NAC-alpha domain-containing protein 1
Synonyms	KIAA0363
Description	FUNCTION: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity). .
Accessions	O15069 ENST00000490531.3

NACAD report