NAA40 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NAA40 at tissue level.

III. Associated gene sets

GO_0006629Biological processlipid metabolic process
GO_0006338Biological processchromatin remodeling
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0034451Cellular componentcentriolar satellite
GO_0005634Cellular componentnucleus
GO_0010485Molecular functionhistone H4 acetyltransferase activity
GO_1990189Molecular functionpeptide-serine-alpha-N-acetyltransferase activity
GO_0043998Molecular functionhistone H2A acetyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNAA40
Protein nameN-alpha-acetyltransferase 40 (EC 2.3.1.257) (N-acetyltransferase 11) (N-alpha-acetyltransferase D) (NatD) (hNatD) (Protein acetyltransferase 1)
N-alpha-acetyltransferase 40, NatD catalytic subunit
N-alpha-acetyltransferase 40 (EC 2.3.1.257)
SynonymsNAT11
PATT1
DescriptionFUNCTION: N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A . In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' . Acts as a negative regulator of apoptosis . May play a role in hepatic lipid metabolism (By similarity). .

AccessionsQ86UY6
ENST00000542163.1 [Q86UY6-3]
F2YHM7
F5H2C9
ENST00000539656.5
F5GXF6
ENST00000534965.5
F5GY41
ENST00000544138.5
ENST00000377793.9 [Q86UY6-1]