MYZAP report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MYZAP at tissue level.

III. Associated gene sets

GO_0035556Biological processintracellular signal transduction
GO_0051685Biological processmaintenance of ER location
GO_0009898Cellular componentcytoplasmic side of plasma membrane
GO_0016591Cellular componentRNA polymerase II, holoenzyme
GO_0031674Cellular componentI band
GO_0005622Cellular componentintracellular anatomical structure
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0070161Cellular componentanchoring junction
GO_0005635Cellular componentnuclear envelope
GO_0030018Cellular componentZ disc
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMYZAP
Protein nameMyocardial zonula adherens protein
Myocardial zonula adherens protein (GRINL1A upstream protein) (Gup)
SynonymsMYOZAP
DescriptionFUNCTION: Plays a role in cellular signaling via Rho-related GTP-binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity). .

AccessionsENST00000569089.1
ENST00000461709.1
ENST00000267853.10 [P0CAP1-1]
ENST00000380565.8 [P0CAP1-4]
H0YCD3
P0CAP1
H3BTD5