I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glial cell | 4 studies | 33% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glial cell | 4 studies | 33% ± 17% |
Insufficient scRNA-seq data for expression of MYOT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 93% | 655.50 | 227 / 245 | 8% | 1.47 | 41 / 502 |
| muscle | 100% | 54494.83 | 803 / 803 | 0% | 0 | 0 / 0 |
| intestine | 97% | 552.08 | 938 / 966 | 1% | 0.01 | 3 / 527 |
| heart | 93% | 1037.26 | 803 / 861 | 0% | 0 | 0 / 0 |
| brain | 81% | 242.03 | 2129 / 2642 | 5% | 0.18 | 38 / 705 |
| bladder | 81% | 234.38 | 17 / 21 | 1% | 0.02 | 4 / 504 |
| adrenal gland | 59% | 87.68 | 151 / 258 | 15% | 0.36 | 34 / 230 |
| esophagus | 71% | 396.04 | 1022 / 1445 | 1% | 0.02 | 2 / 183 |
| blood vessel | 64% | 163.31 | 860 / 1335 | 0% | 0 | 0 / 0 |
| kidney | 34% | 49.31 | 30 / 89 | 18% | 0.35 | 160 / 901 |
| stomach | 43% | 149.73 | 154 / 359 | 1% | 0.01 | 2 / 286 |
| thymus | 38% | 77.42 | 248 / 653 | 1% | 0.10 | 5 / 605 |
| uterus | 29% | 74.59 | 50 / 170 | 5% | 1.42 | 23 / 459 |
| adipose | 27% | 45.13 | 331 / 1204 | 0% | 0 | 0 / 0 |
| breast | 24% | 53.03 | 109 / 459 | 2% | 0.14 | 19 / 1118 |
| spleen | 24% | 34.03 | 57 / 241 | 0% | 0 | 0 / 0 |
| ovary | 13% | 22.03 | 24 / 180 | 1% | 0.02 | 4 / 430 |
| tonsil | 0% | 0 | 0 / 0 | 13% | 1.22 | 6 / 45 |
| skin | 8% | 32.13 | 148 / 1809 | 1% | 0.01 | 4 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.17 | 2 / 29 |
| lung | 3% | 5.61 | 16 / 578 | 2% | 0.06 | 19 / 1155 |
| peripheral blood | 4% | 15.13 | 38 / 929 | 0% | 0 | 0 / 0 |
| pancreas | 2% | 2.60 | 7 / 328 | 1% | 0.04 | 2 / 178 |
| liver | 3% | 3.59 | 7 / 226 | 0% | 0 | 0 / 406 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0006936 | Biological process | muscle contraction |
| GO_0050808 | Biological process | synapse organization |
| GO_0007411 | Biological process | axon guidance |
| GO_0015629 | Cellular component | actin cytoskeleton |
| GO_0030424 | Cellular component | axon |
| GO_0042383 | Cellular component | sarcolemma |
| GO_0030018 | Cellular component | Z disc |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0051393 | Molecular function | alpha-actinin binding |
| GO_0008046 | Molecular function | axon guidance receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003779 | Molecular function | actin binding |
| GO_0008307 | Molecular function | structural constituent of muscle |
| Gene name | MYOT |
| Protein name | Myotilin Myotilin (57 kDa cytoskeletal protein) (Myofibrillar titin-like Ig domains protein) (Titin immunoglobulin domain protein) Myotilin isoform 1 Myotilin isoform 2 |
| Synonyms | hCG_39937 TTID |
| Description | FUNCTION: Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells. . |
| Accessions | A0A0C4DFM5 ENST00000421631.6 [Q9UBF9-2] A0A0S2Z4Y0 ENST00000239926.9 A0A0S2Z522 B4DT68 Q9UBF9 ENST00000515645.1 |
