Name | Number of supported studies | Average coverage | |
---|---|---|---|
cardiac muscle cell | 5 studies | 61% ± 15% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
heart | 3 studies | 29% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
heart | 99% | 14169.69 | 853 / 861 | 0% | 0 | 0 / 0 |
muscle | 98% | 2302.20 | 783 / 803 | 0% | 0 | 0 / 0 |
kidney | 73% | 328.67 | 65 / 89 | 1% | 0.02 | 9 / 901 |
eye | 0% | 0 | 0 / 0 | 45% | 1.29 | 36 / 80 |
brain | 21% | 231.27 | 559 / 2642 | 14% | 0.30 | 96 / 705 |
ovary | 16% | 28.64 | 29 / 180 | 17% | 0.38 | 75 / 430 |
adrenal gland | 1% | 3.10 | 3 / 258 | 24% | 2.00 | 55 / 230 |
lung | 12% | 42.38 | 71 / 578 | 3% | 0.08 | 39 / 1155 |
uterus | 8% | 19.22 | 14 / 170 | 7% | 0.27 | 34 / 459 |
skin | 0% | 0.41 | 2 / 1809 | 14% | 0.47 | 68 / 472 |
prostate | 8% | 47.44 | 19 / 245 | 5% | 0.23 | 24 / 502 |
breast | 2% | 12.96 | 7 / 459 | 3% | 0.08 | 38 / 1118 |
blood vessel | 4% | 36.84 | 53 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
thymus | 1% | 6.84 | 5 / 653 | 2% | 0.05 | 13 / 605 |
peripheral blood | 3% | 6.15 | 24 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.06 | 1 / 45 |
esophagus | 1% | 6.63 | 18 / 1445 | 1% | 0.01 | 1 / 183 |
liver | 0% | 0.63 | 1 / 226 | 1% | 0.02 | 5 / 406 |
bladder | 0% | 0 | 0 / 21 | 1% | 0.04 | 6 / 504 |
stomach | 0% | 0 | 0 / 359 | 1% | 0.01 | 3 / 286 |
pancreas | 0% | 0.44 | 1 / 328 | 1% | 0.01 | 1 / 178 |
adipose | 1% | 1.87 | 7 / 1204 | 0% | 0 | 0 / 0 |
spleen | 0% | 0.55 | 1 / 241 | 0% | 0 | 0 / 0 |
intestine | 0% | 0.48 | 2 / 966 | 0% | 0.00 | 1 / 527 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0045214 | Biological process | sarcomere organization |
GO_0006468 | Biological process | protein phosphorylation |
GO_0060298 | Biological process | positive regulation of sarcomere organization |
GO_0071347 | Biological process | cellular response to interleukin-1 |
GO_0048769 | Biological process | sarcomerogenesis |
GO_0002528 | Biological process | regulation of vascular permeability involved in acute inflammatory response |
GO_0055003 | Biological process | cardiac myofibril assembly |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0004683 | Molecular function | calmodulin-dependent protein kinase activity |
GO_0004687 | Molecular function | myosin light chain kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | MYLK3 |
Protein name | Alternative protein MYLK3 Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK) |
Synonyms | MLCK |
Description | FUNCTION: Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity). . |
Accessions | L8E9T3 Q32MK0 ENST00000536476.5 [Q32MK0-4] ENST00000394809.9 [Q32MK0-3] |