Insufficient scRNA-seq data for expression of MYCNOS at single-cell level.
Insufficient scRNA-seq data for expression of MYCNOS at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 90% | 16.04 | 2370 / 2642 | 37% | 0.69 | 258 / 705 |
ovary | 84% | 12.47 | 151 / 180 | 16% | 0.30 | 70 / 430 |
thymus | 90% | 10.80 | 586 / 653 | 3% | 0.04 | 16 / 605 |
kidney | 58% | 6.78 | 52 / 89 | 0% | 0.01 | 1 / 901 |
stomach | 51% | 3.24 | 182 / 359 | 2% | 0.06 | 6 / 286 |
bladder | 24% | 1.00 | 5 / 21 | 9% | 0.27 | 44 / 504 |
skin | 18% | 1.67 | 331 / 1809 | 12% | 0.53 | 58 / 472 |
uterus | 16% | 0.65 | 27 / 170 | 5% | 0.13 | 25 / 459 |
liver | 20% | 1.63 | 45 / 226 | 1% | 0.01 | 4 / 406 |
intestine | 17% | 0.73 | 168 / 966 | 0% | 0.03 | 2 / 527 |
esophagus | 12% | 0.54 | 180 / 1445 | 4% | 0.10 | 8 / 183 |
adrenal gland | 11% | 0.56 | 28 / 258 | 6% | 0.07 | 13 / 230 |
breast | 14% | 0.72 | 66 / 459 | 1% | 0.01 | 7 / 1118 |
spleen | 11% | 0.48 | 27 / 241 | 0% | 0 | 0 / 0 |
heart | 11% | 0.45 | 94 / 861 | 0% | 0 | 0 / 0 |
adipose | 10% | 0.50 | 122 / 1204 | 0% | 0 | 0 / 0 |
lung | 4% | 0.19 | 25 / 578 | 4% | 0.12 | 41 / 1155 |
blood vessel | 5% | 0.20 | 63 / 1335 | 0% | 0 | 0 / 0 |
prostate | 4% | 0.29 | 11 / 245 | 0% | 0 | 0 / 502 |
eye | 0% | 0 | 0 / 0 | 3% | 0.04 | 2 / 80 |
peripheral blood | 2% | 0.11 | 23 / 929 | 0% | 0 | 0 / 0 |
pancreas | 2% | 0.07 | 7 / 328 | 0% | 0 | 0 / 178 |
muscle | 1% | 0.06 | 11 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0033673 | Biological process | negative regulation of kinase activity |
GO_0031647 | Biological process | regulation of protein stability |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
Gene name | MYCNOS |
Protein name | N-cym protein (N-myc opposite strand) |
Synonyms | NCYM CYMN |
Description | FUNCTION: Regulates stability of MYCN in neuroblastoma cells by inhibiting GSK3B-mediated MYCN phosphorylation. Inhibits GSK3B activity by promoting its phosphorylation at 'Ser-9' . . |
Accessions | P40205 |