MYBPC3 | OmnibusX

Name	Number of supported studies	Average coverage
cardiac muscle cell	7 studies	81% ± 26%	Explore

Name	Number of supported studies	Average coverage
heart	6 studies	34% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	99%	609.24	255 / 258	25%	2.78	57 / 230
lung	97%	450.61	562 / 578	3%	0.05	33 / 1155
heart	100%	188411.10	861 / 861	0%	0	0 / 0
spleen	100%	685.48	241 / 241	0%	0	0 / 0
peripheral blood	86%	1131.04	797 / 929	0%	0	0 / 0
stomach	80%	432.11	286 / 359	6%	0.39	17 / 286
adipose	46%	89.33	554 / 1204	0%	0	0 / 0
intestine	26%	30.74	247 / 966	3%	0.07	17 / 527
breast	25%	115.25	114 / 459	1%	0.05	12 / 1118
kidney	24%	28.52	21 / 89	1%	0.02	10 / 901
blood vessel	22%	521.83	300 / 1335	0%	0	0 / 0
thymus	22%	50.91	141 / 653	0%	0.01	3 / 605
muscle	22%	28.30	177 / 803	0%	0	0 / 0
esophagus	16%	21.48	224 / 1445	6%	0.13	11 / 183
prostate	16%	82.36	40 / 245	1%	0.05	4 / 502
bladder	14%	12.19	3 / 21	2%	0.02	9 / 504
liver	15%	18.81	34 / 226	1%	0.12	4 / 406
skin	15%	22.21	279 / 1809	0%	0.01	2 / 472
brain	13%	19.96	344 / 2642	0%	0.01	3 / 705
ovary	12%	15.04	22 / 180	0%	0	0 / 430
uterus	9%	14.95	15 / 170	3%	0.12	14 / 459
tonsil	0%	0	0 / 0	11%	0.17	5 / 45
pancreas	7%	16.02	23 / 328	4%	0.06	7 / 178
lymph node	0%	0	0 / 0	10%	0.15	3 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006942	Biological process	regulation of striated muscle contraction
GO_0032781	Biological process	positive regulation of ATP-dependent activity
GO_0007155	Biological process	cell adhesion
GO_0032971	Biological process	regulation of muscle filament sliding
GO_0060048	Biological process	cardiac muscle contraction
GO_0055010	Biological process	ventricular cardiac muscle tissue morphogenesis
GO_0003007	Biological process	heart morphogenesis
GO_0045214	Biological process	sarcomere organization
GO_0097512	Cellular component	cardiac myofibril
GO_0005863	Cellular component	striated muscle myosin thick filament
GO_0030017	Cellular component	sarcomere
GO_0005829	Cellular component	cytosol
GO_0031672	Cellular component	A band
GO_0031430	Cellular component	M band
GO_0014705	Cellular component	C zone
GO_0008307	Molecular function	structural constituent of muscle
GO_0031432	Molecular function	titin binding
GO_0017022	Molecular function	myosin binding
GO_0032036	Molecular function	myosin heavy chain binding
GO_0042802	Molecular function	identical protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding
GO_0003779	Molecular function	actin binding
GO_0001671	Molecular function	ATPase activator activity

Gene name	MYBPC3
Protein name	Truncated cardiac myosin-binding protein C Myosin-binding protein C Myosin binding protein C, cardiac Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform) Mutant cardiac myosin-binding protein C Myosin binding protein C3 Myosin-binding protein C, cardiac-type (C-protein, cardiac muscle isoform) Myosin-binding protein C cardiac
Synonyms
Description	FUNCTION: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Accessions	B6D425 ENST00000545968.6 [Q14896-1] A0A1B1HY24 A0A411J1F3 B6D426 A0A1B1HY15 A0A7R6RQ59 A5YM48 Q14896 A0A1B1HY19 A0A1B1HY20 F5GZR4 ENST00000544791.1 ENST00000399249.6 A0A191TDH5 A0A1B1HY14 A0A1B1HY25 A8MXZ9

MYBPC3 report