MYBPC2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MYBPC2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MYBPC2 at tissue level.

III. Associated gene sets

GO_0045214Biological processsarcomere organization
GO_0007155Biological processcell adhesion
GO_0031430Cellular componentM band
GO_0005829Cellular componentcytosol
GO_0032982Cellular componentmyosin filament
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding
GO_0008307Molecular functionstructural constituent of muscle

IV. Literature review

[source]
Gene nameMYBPC2
Protein nameMyosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)
SynonymsMYBPCF
DescriptionFUNCTION: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.

AccessionsENST00000357701.6
Q14324