MVK | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	5 studies	26% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of MVK at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2742.52	258 / 258	100%	34.23	230 / 230
thymus	100%	1740.38	653 / 653	100%	14.91	604 / 605
liver	100%	3670.36	226 / 226	100%	20.43	405 / 406
kidney	100%	2521.88	89 / 89	100%	20.82	898 / 901
prostate	100%	1374.53	245 / 245	99%	17.22	499 / 502
uterus	99%	841.83	169 / 170	100%	16.74	458 / 459
bladder	100%	952.48	21 / 21	99%	17.50	498 / 504
brain	99%	1068.59	2603 / 2642	100%	10.38	705 / 705
esophagus	100%	1859.79	1439 / 1445	99%	10.02	181 / 183
intestine	100%	950.34	964 / 966	99%	12.54	520 / 527
skin	100%	2370.55	1800 / 1809	99%	11.30	466 / 472
ovary	100%	1054.93	180 / 180	98%	8.79	422 / 430
breast	98%	902.16	451 / 459	99%	12.04	1108 / 1118
stomach	98%	880.21	353 / 359	98%	10.43	279 / 286
lung	94%	1072.72	541 / 578	98%	12.59	1135 / 1155
pancreas	91%	533.11	300 / 328	98%	9.42	175 / 178
eye	0%	0	0 / 0	100%	9.22	80 / 80
lymph node	0%	0	0 / 0	100%	11.55	29 / 29
tonsil	0%	0	0 / 0	100%	19.35	45 / 45
ureter	0%	0	0 / 0	100%	37.13	1 / 1
spleen	100%	713.57	240 / 241	0%	0	0 / 0
blood vessel	98%	691.47	1308 / 1335	0%	0	0 / 0
adipose	98%	739.16	1178 / 1204	0%	0	0 / 0
muscle	96%	653.45	767 / 803	0%	0	0 / 0
heart	91%	514.76	784 / 861	0%	0	0 / 0
peripheral blood	50%	550.46	464 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0008299	Biological process	isoprenoid biosynthetic process
GO_0050728	Biological process	negative regulation of inflammatory response
GO_0006695	Biological process	cholesterol biosynthetic process
GO_0019287	Biological process	isopentenyl diphosphate biosynthetic process, mevalonate pathway
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005829	Cellular component	cytosol
GO_0005777	Cellular component	peroxisome
GO_0004496	Molecular function	mevalonate kinase activity
GO_0005524	Molecular function	ATP binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0000287	Molecular function	magnesium ion binding

Gene name	MVK
Protein name	Mevalonate kinase (MK) (EC 2.7.1.36) mevalonate kinase (EC 2.7.1.36) Mevalonate kinase (Mevalonic aciduria), isoform CRA_a (cDNA FLJ57872, highly similar to Mevalonate kinase) Mevalonate kinase
Synonyms	hCG_40321
Description	FUNCTION: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis . . FUNCTION: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis. . FUNCTION: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis. . FUNCTION: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis. .
Accessions	A0A8V8TMD0 ENST00000636996.1 B2RDU6 ENST00000228510.8 F5H368 ENST00000392727.7 ENST00000697196.1 B7Z1C2 F5GXC0 F5H092 A0A1B0GWC2 ENST00000447878.6 ENST00000545774.5 ENST00000546277.5 Q03426 F5H163 A0A0B4J236 F5H8H2 ENST00000546277.6 ENST00000697195.1 ENST00000539696.6 ENST00000539335.5 ENST00000537237.5

MVK report