I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| respiratory goblet cell | 6 studies | 54% ± 17% | |
| deuterosomal cell | 4 studies | 25% ± 11% | |
| club cell | 3 studies | 22% ± 5% | |
| goblet cell | 3 studies | 50% ± 32% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| respiratory goblet cell | 6 studies | 54% ± 17% | |
| deuterosomal cell | 4 studies | 25% ± 11% | |
| club cell | 3 studies | 22% ± 5% | |
| goblet cell | 3 studies | 50% ± 32% |
Insufficient scRNA-seq data for expression of MUC5AC at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 98% | 101318.56 | 352 / 359 | 62% | 73.65 | 177 / 286 |
| pancreas | 77% | 396.65 | 252 / 328 | 79% | 74.96 | 141 / 178 |
| lung | 89% | 1162.14 | 515 / 578 | 36% | 58.68 | 411 / 1155 |
| intestine | 63% | 67.80 | 606 / 966 | 53% | 56.28 | 280 / 527 |
| esophagus | 62% | 168.17 | 895 / 1445 | 46% | 86.51 | 84 / 183 |
| ureter | 0% | 0 | 0 / 0 | 100% | 52.63 | 1 / 1 |
| bladder | 71% | 34.48 | 15 / 21 | 22% | 4.36 | 110 / 504 |
| prostate | 89% | 91.42 | 219 / 245 | 2% | 0.07 | 9 / 502 |
| uterus | 66% | 105.34 | 113 / 170 | 22% | 16.05 | 103 / 459 |
| spleen | 70% | 15.49 | 169 / 241 | 0% | 0 | 0 / 0 |
| ovary | 59% | 11.95 | 106 / 180 | 10% | 0.43 | 43 / 430 |
| liver | 64% | 23.16 | 145 / 226 | 2% | 1.74 | 9 / 406 |
| adrenal gland | 64% | 14.98 | 165 / 258 | 0% | 0 | 0 / 230 |
| breast | 50% | 50.17 | 231 / 459 | 5% | 1.57 | 54 / 1118 |
| muscle | 49% | 14.41 | 397 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 48% | 36.30 | 445 / 929 | 0% | 0 | 0 / 0 |
| skin | 47% | 11.05 | 856 / 1809 | 0% | 0.04 | 1 / 472 |
| blood vessel | 47% | 12.91 | 630 / 1335 | 0% | 0 | 0 / 0 |
| kidney | 47% | 6.94 | 42 / 89 | 0% | 0 | 0 / 901 |
| adipose | 46% | 63.05 | 549 / 1204 | 0% | 0 | 0 / 0 |
| thymus | 44% | 9.01 | 285 / 653 | 0% | 0.00 | 1 / 605 |
| brain | 42% | 10.02 | 1106 / 2642 | 0% | 0.00 | 1 / 705 |
| heart | 33% | 12.38 | 284 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.04 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005796 | Cellular component | Golgi lumen |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0070701 | Cellular component | mucus layer |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0005201 | Molecular function | extracellular matrix structural constituent |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | MUC5AC |
| Protein name | Gastric mucin MUC5AC protein MUC5AC Mucin 5AC, oligomeric mucus/gel-forming Mucin-5AC (MUC-5AC) (Gastric mucin) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM) Mucin |
| Synonyms | MUC5 |
| Description | FUNCTION: Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system . Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD) . . |
| Accessions | Q14890 O75372 ENST00000621226.2 Q14851 T1R7M6 T1R7A8 T1S9D5 A7Y9J9 T1R7N3 Q14888 T1R7Q9 P98088 H9XFC1 Q14891 Q96DU6 ENST00000707307.1 Q14892 Q14887 T1R7N1 Q14893 Q14886 Q14889 |
