I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 26% ± 7% | |
| GABAergic neuron | 3 studies | 29% ± 7% | |
| interneuron | 3 studies | 36% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 26% ± 7% | |
| GABAergic neuron | 3 studies | 29% ± 7% | |
| interneuron | 3 studies | 36% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 22% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 78.92 | 965 / 966 | 79% | 2.02 | 416 / 527 |
| stomach | 100% | 56.97 | 358 / 359 | 75% | 2.20 | 215 / 286 |
| bladder | 100% | 111.81 | 21 / 21 | 64% | 1.52 | 323 / 504 |
| adrenal gland | 100% | 58.02 | 258 / 258 | 60% | 1.16 | 138 / 230 |
| pancreas | 93% | 29.91 | 306 / 328 | 64% | 1.13 | 114 / 178 |
| esophagus | 100% | 70.20 | 1442 / 1445 | 57% | 1.38 | 105 / 183 |
| thymus | 100% | 65.98 | 653 / 653 | 54% | 0.78 | 325 / 605 |
| uterus | 100% | 80.72 | 170 / 170 | 50% | 1.11 | 231 / 459 |
| lung | 100% | 57.63 | 576 / 578 | 47% | 0.92 | 548 / 1155 |
| ovary | 100% | 123.91 | 180 / 180 | 46% | 0.75 | 197 / 430 |
| kidney | 100% | 52.69 | 89 / 89 | 41% | 0.66 | 365 / 901 |
| prostate | 100% | 92.84 | 245 / 245 | 29% | 0.46 | 145 / 502 |
| breast | 99% | 59.43 | 456 / 459 | 27% | 0.48 | 303 / 1118 |
| skin | 76% | 38.96 | 1368 / 1809 | 45% | 0.97 | 214 / 472 |
| spleen | 100% | 67.88 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 118.57 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 98% | 52.98 | 1181 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 2.18 | 24 / 29 |
| muscle | 81% | 21.45 | 653 / 803 | 0% | 0 | 0 / 0 |
| brain | 68% | 17.03 | 1801 / 2642 | 12% | 0.19 | 82 / 705 |
| peripheral blood | 77% | 58.29 | 719 / 929 | 0% | 0 | 0 / 0 |
| heart | 77% | 23.03 | 660 / 861 | 0% | 0 | 0 / 0 |
| liver | 60% | 12.42 | 136 / 226 | 11% | 0.15 | 43 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 1.26 | 23 / 45 |
| eye | 0% | 0 | 0 / 0 | 25% | 0.33 | 20 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016241 | Biological process | regulation of macroautophagy |
| GO_0046856 | Biological process | phosphatidylinositol dephosphorylation |
| GO_0005829 | Cellular component | cytosol |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004438 | Molecular function | phosphatidylinositol-3-phosphate phosphatase activity |
| GO_0106018 | Molecular function | phosphatidylinositol-3,5-bisphosphate phosphatase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0052629 | Molecular function | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity |
| Gene name | MTMR8 |
| Protein name | Myotubularin-related protein 8 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) |
| Synonyms | |
| Description | FUNCTION: Phosphatase that acts on lipids with a phosphoinositol headgroup . Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate . In complex with MTMR9, negatively regulates autophagy . . |
| Accessions | ENST00000374852.4 [Q96EF0-1] Q96EF0 |
