MTMR4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006470Biological processprotein dephosphorylation
GO_0030512Biological processnegative regulation of transforming growth factor beta receptor signaling pathway
GO_0046856Biological processphosphatidylinositol dephosphorylation
GO_0030514Biological processnegative regulation of BMP signaling pathway
GO_0010506Biological processregulation of autophagy
GO_0060304Biological processregulation of phosphatidylinositol dephosphorylation
GO_0006661Biological processphosphatidylinositol biosynthetic process
GO_0005615Cellular componentextracellular space
GO_0016020Cellular componentmembrane
GO_0031901Cellular componentearly endosome membrane
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005768Cellular componentendosome
GO_0004438Molecular functionphosphatidylinositol-3-phosphate phosphatase activity
GO_0019903Molecular functionprotein phosphatase binding
GO_0052629Molecular functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
GO_0046872Molecular functionmetal ion binding
GO_0004722Molecular functionprotein serine/threonine phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameMTMR4
Protein nameMyotubularin related protein 4
protein-tyrosine-phosphatase (EC 3.1.3.48)
Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11)
SynonymsKIAA0647
ZFYVE11
DescriptionFUNCTION: Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3). .

AccessionsENST00000323456.9
A0A804HJV7
ENST00000682306.1
ENST00000582390.5
ENST00000579921.1
J3QRJ2
ENST00000582663.5
J3QR65
ENST00000579925.5
Q9NYA4
J3KT95
J3QKV8