Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 16 studies | 26% ± 11% | |
pericyte | 14 studies | 47% ± 26% | |
smooth muscle cell | 11 studies | 53% ± 26% | |
capillary endothelial cell | 5 studies | 30% ± 7% | |
endothelial cell of artery | 5 studies | 37% ± 14% | |
endothelial cell of vascular tree | 5 studies | 36% ± 21% | |
endothelial cell | 4 studies | 21% ± 5% | |
adventitial cell | 4 studies | 29% ± 12% | |
vein endothelial cell | 3 studies | 35% ± 15% | |
connective tissue cell | 3 studies | 29% ± 5% | |
hepatocyte | 3 studies | 48% ± 11% |
Insufficient scRNA-seq data for expression of MT1A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 92% | 2269.96 | 208 / 226 | 82% | 88.62 | 331 / 406 |
breast | 83% | 1824.63 | 380 / 459 | 47% | 16.11 | 525 / 1118 |
lung | 81% | 1041.14 | 469 / 578 | 40% | 12.02 | 465 / 1155 |
pancreas | 38% | 160.20 | 124 / 328 | 81% | 25.20 | 145 / 178 |
adrenal gland | 64% | 551.85 | 166 / 258 | 50% | 22.76 | 115 / 230 |
thymus | 72% | 696.21 | 470 / 653 | 38% | 4.99 | 229 / 605 |
prostate | 40% | 284.07 | 98 / 245 | 68% | 15.03 | 343 / 502 |
stomach | 58% | 341.74 | 209 / 359 | 50% | 11.62 | 143 / 286 |
ovary | 37% | 168.39 | 67 / 180 | 63% | 18.71 | 269 / 430 |
kidney | 47% | 304.97 | 42 / 89 | 49% | 12.95 | 441 / 901 |
intestine | 39% | 224.16 | 372 / 966 | 56% | 14.27 | 296 / 527 |
skin | 46% | 260.89 | 825 / 1809 | 49% | 22.42 | 231 / 472 |
bladder | 57% | 330.38 | 12 / 21 | 37% | 9.79 | 185 / 504 |
adipose | 88% | 2917.68 | 1061 / 1204 | 0% | 0 | 0 / 0 |
esophagus | 40% | 319.65 | 580 / 1445 | 41% | 9.39 | 75 / 183 |
blood vessel | 74% | 798.28 | 990 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 70% | 8.68 | 56 / 80 |
uterus | 33% | 265.35 | 56 / 170 | 30% | 9.60 | 136 / 459 |
brain | 21% | 72.55 | 559 / 2642 | 36% | 5.07 | 251 / 705 |
heart | 44% | 337.13 | 381 / 861 | 0% | 0 | 0 / 0 |
muscle | 42% | 493.40 | 336 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.64 | 3 / 29 |
spleen | 5% | 12.02 | 12 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 3% | 14.47 | 24 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.16 | 1 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0071294 | Biological process | cellular response to zinc ion |
GO_0071276 | Biological process | cellular response to cadmium ion |
GO_0071280 | Biological process | cellular response to copper ion |
GO_0010273 | Biological process | detoxification of copper ion |
GO_0045926 | Biological process | negative regulation of growth |
GO_0006882 | Biological process | intracellular zinc ion homeostasis |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | MT1A |
Protein name | Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA) |
Synonyms | MT1S |
Description | FUNCTION: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. |
Accessions | ENST00000290705.12 P04731 |