Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 15 studies | 24% ± 10% | |
| smooth muscle cell | 13 studies | 25% ± 9% | |
| pericyte | 8 studies | 20% ± 4% | |
| epithelial cell | 7 studies | 36% ± 20% | |
| myofibroblast cell | 6 studies | 25% ± 3% | |
| connective tissue cell | 6 studies | 22% ± 5% | |
| epithelial cell of proximal tubule | 5 studies | 26% ± 7% | |
| ciliated cell | 5 studies | 36% ± 12% | |
| macrophage | 5 studies | 23% ± 6% | |
| retinal ganglion cell | 4 studies | 54% ± 24% | |
| astrocyte | 4 studies | 25% ± 8% | |
| retina horizontal cell | 4 studies | 37% ± 13% | |
| endothelial cell | 4 studies | 26% ± 5% | |
| neuron | 4 studies | 37% ± 11% | |
| oligodendrocyte precursor cell | 4 studies | 26% ± 5% | |
| hematopoietic precursor cell | 3 studies | 20% ± 6% | |
| retinal bipolar neuron | 3 studies | 29% ± 9% | |
| myeloid cell | 3 studies | 24% ± 8% | |
| amacrine cell | 3 studies | 32% ± 11% | |
| GABAergic neuron | 3 studies | 27% ± 8% | |
| glutamatergic neuron | 3 studies | 30% ± 13% | |
| abnormal cell | 3 studies | 17% ± 1% | |
| brush cell | 3 studies | 31% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 1921.94 | 89 / 89 | 100% | 59.21 | 901 / 901 |
| liver | 100% | 1885.94 | 226 / 226 | 100% | 69.34 | 406 / 406 |
| thymus | 100% | 1835.73 | 653 / 653 | 100% | 56.53 | 605 / 605 |
| brain | 100% | 1948.77 | 2641 / 2642 | 100% | 48.19 | 705 / 705 |
| prostate | 100% | 1835.42 | 245 / 245 | 100% | 55.95 | 501 / 502 |
| ovary | 100% | 1261.92 | 180 / 180 | 100% | 51.42 | 429 / 430 |
| adrenal gland | 100% | 1989.86 | 258 / 258 | 100% | 59.47 | 229 / 230 |
| intestine | 100% | 2054.26 | 965 / 966 | 100% | 53.81 | 525 / 527 |
| breast | 100% | 1265.32 | 459 / 459 | 99% | 55.71 | 1112 / 1118 |
| lung | 99% | 1183.34 | 574 / 578 | 100% | 35.36 | 1152 / 1155 |
| esophagus | 100% | 1883.33 | 1445 / 1445 | 99% | 28.45 | 181 / 183 |
| stomach | 98% | 1073.50 | 352 / 359 | 100% | 48.22 | 286 / 286 |
| uterus | 100% | 1787.99 | 170 / 170 | 98% | 47.22 | 449 / 459 |
| bladder | 100% | 1967.52 | 21 / 21 | 98% | 44.66 | 493 / 504 |
| skin | 97% | 899.69 | 1751 / 1809 | 100% | 60.80 | 471 / 472 |
| pancreas | 45% | 220.79 | 149 / 328 | 99% | 45.47 | 176 / 178 |
| adipose | 100% | 1380.72 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 53.12 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 42.08 | 29 / 29 |
| spleen | 100% | 1147.67 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 33.30 | 1 / 1 |
| muscle | 100% | 2010.45 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1717.54 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 4100.75 | 855 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 21.47 | 41 / 45 |
| peripheral blood | 81% | 953.77 | 755 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030041 | Biological process | actin filament polymerization |
| GO_0030091 | Biological process | protein repair |
| GO_0006979 | Biological process | response to oxidative stress |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0033745 | Molecular function | L-methionine-(R)-S-oxide reductase activity |
| GO_0033743 | Molecular function | peptide-methionine (R)-S-oxide reductase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003779 | Molecular function | actin binding |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | MSRB2 |
| Protein name | Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.12) (EC 1.8.4.14) Methionine sulfoxide reductase B2 Methionine sulfoxide reductase B2, isoform CRA_a (Methionine-r-sulfoxide reductase B2 variant 1) |
| Synonyms | MSRB CGI-131 CBS-1 hCG_23087 |
| Description | FUNCTION: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. . |
| Accessions | H0YE51 ENST00000376510.8 Q9Y3D2 ENST00000472663.1 A6NCQ5 |