Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 9 studies | 24% ± 12% | |
| retinal rod cell | 3 studies | 33% ± 14% |
Insufficient scRNA-seq data for expression of MRLN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| muscle | 100% | 2190.05 | 803 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 31% | 1.44 | 14 / 45 |
| pancreas | 4% | 3.14 | 14 / 328 | 26% | 0.99 | 47 / 178 |
| uterus | 1% | 1.76 | 2 / 170 | 27% | 2.97 | 125 / 459 |
| esophagus | 1% | 0.64 | 10 / 1445 | 27% | 1.65 | 50 / 183 |
| kidney | 21% | 34.55 | 19 / 89 | 4% | 0.11 | 35 / 901 |
| brain | 18% | 123.86 | 473 / 2642 | 0% | 0.00 | 1 / 705 |
| lung | 2% | 1.81 | 11 / 578 | 9% | 0.37 | 102 / 1155 |
| intestine | 0% | 0.09 | 1 / 966 | 10% | 0.63 | 52 / 527 |
| ovary | 0% | 0 | 0 / 180 | 6% | 0.19 | 26 / 430 |
| stomach | 0% | 0 | 0 / 359 | 6% | 0.31 | 16 / 286 |
| bladder | 0% | 0 | 0 / 21 | 5% | 0.29 | 26 / 504 |
| prostate | 4% | 4.24 | 9 / 245 | 1% | 0.03 | 6 / 502 |
| adrenal gland | 0% | 0.33 | 1 / 258 | 2% | 0.25 | 5 / 230 |
| breast | 1% | 1.20 | 5 / 459 | 1% | 0.03 | 7 / 1118 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.04 | 1 / 80 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.10 | 5 / 406 |
| skin | 0% | 0.91 | 1 / 1809 | 1% | 0.03 | 4 / 472 |
| peripheral blood | 1% | 1.15 | 5 / 929 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0.17 | 1 / 653 | 0% | 0.00 | 1 / 605 |
| adipose | 0% | 0.27 | 3 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.95 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1902081 | Biological process | negative regulation of calcium ion import into sarcoplasmic reticulum |
| GO_0033017 | Cellular component | sarcoplasmic reticulum membrane |
| GO_0004857 | Molecular function | enzyme inhibitor activity |
| Gene name | MRLN |
| Protein name | Myoregulin |
| Synonyms | MLN |
| Description | FUNCTION: Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+), thereby acting as a key regulator of skeletal muscle activity. Its high expression in adult skeletal muscle, suggests that it constitutes the predominant regulator of ATP2A1/SERCA1 in adult skeletal muscle. . |
| Accessions | ENST00000594536.5 ENST00000430431.5 ENST00000628562.1 P0DMT0 ENST00000414264.6 |