MRLN report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MRLN at tissue level.

III. Associated gene sets

GO_1902081Biological processnegative regulation of calcium ion import into sarcoplasmic reticulum
GO_0033017Cellular componentsarcoplasmic reticulum membrane
GO_0004857Molecular functionenzyme inhibitor activity

IV. Literature review

[source]
Gene nameMRLN
Protein nameMyoregulin
SynonymsMLN
DescriptionFUNCTION: Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+), thereby acting as a key regulator of skeletal muscle activity. Its high expression in adult skeletal muscle, suggests that it constitutes the predominant regulator of ATP2A1/SERCA1 in adult skeletal muscle. .

AccessionsENST00000594536.5
ENST00000430431.5
ENST00000628562.1
P0DMT0
ENST00000414264.6