MRI1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0019509Biological processL-methionine salvage from methylthioadenosine
GO_0019284Biological processL-methionine salvage from S-adenosylmethionine
GO_0042995Cellular componentcell projection
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0001650Cellular componentfibrillar center
GO_0046523Molecular functionS-methyl-5-thioribose-1-phosphate isomerase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMRI1
Protein nameMethylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)
SynonymsUNQ6390/PRO21135
MRDI
DescriptionFUNCTION: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. .

AccessionsQ9BV20
ENST00000319545.12 [Q9BV20-2]
ENST00000040663.8 [Q9BV20-1]