MPPE1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0006506Biological processGPI anchor biosynthetic process
GO_0033116Cellular componentendoplasmic reticulum-Golgi intermediate compartment membrane
GO_0005801Cellular componentcis-Golgi network
GO_0005654Cellular componentnucleoplasm
GO_0005794Cellular componentGolgi apparatus
GO_0070971Cellular componentendoplasmic reticulum exit site
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0030145Molecular functionmanganese ion binding
GO_0062050Molecular functionGPI-mannose ethanolamine phosphate phosphodiesterase activity
GO_0034235Molecular functionGPI anchor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMPPE1
Protein nameMetallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5)
Metallophosphoesterase 1
Metallophosphoesterase 1 (Post-GPI attachment to proteins factor 5)
SynonymsPP579
PGAP5
DescriptionFUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. .

FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. .

FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. .

FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. .

FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. .

FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. .

FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. .

AccessionsENST00000592306.5
ENST00000592977.5
K7ERI3
A0A0C4DH11
K7ER13
ENST00000586844.5
ENST00000317251.8
ENST00000589267.5
ENST00000588191.5
ENST00000344987.11
K7EQ74
A0A075B777
ENST00000588186.5
ENST00000588103.5
ENST00000592331.5
ENST00000593001.5
ENST00000309976.13 [Q53F39-4]
ENST00000587724.5
K7EQV4
ENST00000496196.5 [Q53F39-2]
Q53F39
K7EQ70
K7ELZ7
ENST00000588072.6 [Q53F39-1]
ENST00000589859.1
ENST00000590501.5
K7EJU0
K7ES91
ENST00000317235.11 [Q53F39-4]
K7EM03
K7EIQ0
K7ESB8
A0A0A0MR93