Name | Number of supported studies | Average coverage | |
---|---|---|---|
CD16-positive, CD56-dim natural killer cell, human | 7 studies | 18% ± 2% | |
natural killer cell | 6 studies | 19% ± 4% | |
type I pneumocyte | 6 studies | 19% ± 4% | |
classical monocyte | 4 studies | 22% ± 4% | |
epithelial cell | 4 studies | 27% ± 8% | |
ciliated cell | 4 studies | 20% ± 4% | |
oligodendrocyte | 4 studies | 19% ± 3% | |
CD4-positive, alpha-beta T cell | 3 studies | 16% ± 0% | |
GABAergic neuron | 3 studies | 38% ± 2% | |
astrocyte | 3 studies | 20% ± 4% | |
glutamatergic neuron | 3 studies | 45% ± 12% | |
microglial cell | 3 studies | 26% ± 1% | |
oligodendrocyte precursor cell | 3 studies | 21% ± 3% | |
dendritic cell | 3 studies | 33% ± 12% | |
macrophage | 3 studies | 18% ± 2% | |
basal cell | 3 studies | 23% ± 1% | |
plasmacytoid dendritic cell | 3 studies | 25% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 35% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 677.89 | 328 / 328 | 99% | 6.98 | 177 / 178 |
lung | 100% | 1147.35 | 578 / 578 | 98% | 7.40 | 1137 / 1155 |
thymus | 100% | 1408.80 | 653 / 653 | 98% | 10.62 | 592 / 605 |
esophagus | 100% | 646.80 | 1445 / 1445 | 98% | 5.88 | 179 / 183 |
brain | 99% | 502.05 | 2606 / 2642 | 99% | 6.75 | 699 / 705 |
breast | 100% | 862.47 | 459 / 459 | 98% | 7.38 | 1091 / 1118 |
stomach | 100% | 732.60 | 359 / 359 | 98% | 4.88 | 279 / 286 |
kidney | 100% | 941.17 | 89 / 89 | 97% | 8.93 | 876 / 901 |
intestine | 100% | 863.57 | 966 / 966 | 97% | 5.19 | 509 / 527 |
skin | 100% | 1048.93 | 1809 / 1809 | 96% | 5.67 | 452 / 472 |
uterus | 100% | 838.58 | 170 / 170 | 95% | 6.21 | 438 / 459 |
prostate | 100% | 749.09 | 245 / 245 | 94% | 5.43 | 474 / 502 |
bladder | 100% | 723.71 | 21 / 21 | 94% | 5.13 | 472 / 504 |
ovary | 100% | 629.97 | 180 / 180 | 92% | 4.83 | 395 / 430 |
liver | 100% | 579.60 | 226 / 226 | 89% | 5.32 | 362 / 406 |
adrenal gland | 100% | 709.58 | 257 / 258 | 83% | 4.59 | 191 / 230 |
adipose | 100% | 814.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 737.06 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1091.44 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.27 | 1 / 1 |
blood vessel | 100% | 811.88 | 1331 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 1352.45 | 923 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 603.60 | 844 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 5.77 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 5.45 | 27 / 29 |
eye | 0% | 0 | 0 / 0 | 85% | 3.75 | 68 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
GO_0006506 | Biological process | GPI anchor biosynthetic process |
GO_0033116 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment membrane |
GO_0005801 | Cellular component | cis-Golgi network |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0070971 | Cellular component | endoplasmic reticulum exit site |
GO_0005793 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment |
GO_0030145 | Molecular function | manganese ion binding |
GO_0062050 | Molecular function | GPI-mannose ethanolamine phosphate phosphodiesterase activity |
GO_0034235 | Molecular function | GPI anchor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MPPE1 |
Protein name | Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) Metallophosphoesterase 1 Metallophosphoesterase 1 (Post-GPI attachment to proteins factor 5) |
Synonyms | PP579 PGAP5 |
Description | FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. . FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. . FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. . FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. . FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. . FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. . FUNCTION: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. . |
Accessions | ENST00000592306.5 ENST00000592977.5 K7ERI3 A0A0C4DH11 K7ER13 ENST00000586844.5 ENST00000317251.8 ENST00000589267.5 ENST00000588191.5 ENST00000344987.11 K7EQ74 A0A075B777 ENST00000588186.5 ENST00000588103.5 ENST00000592331.5 ENST00000593001.5 ENST00000309976.13 [Q53F39-4] ENST00000587724.5 K7EQV4 ENST00000496196.5 [Q53F39-2] Q53F39 K7EQ70 K7ELZ7 ENST00000588072.6 [Q53F39-1] ENST00000589859.1 ENST00000590501.5 K7EJU0 K7ES91 ENST00000317235.11 [Q53F39-4] K7EM03 K7EIQ0 K7ESB8 A0A0A0MR93 |