Name | Number of supported studies | Average coverage | |
---|---|---|---|
kidney loop of Henle epithelial cell | 6 studies | 33% ± 10% | |
epithelial cell of proximal tubule | 5 studies | 24% ± 5% | |
epithelial cell | 5 studies | 37% ± 13% | |
endothelial cell | 5 studies | 27% ± 7% | |
fibroblast | 5 studies | 30% ± 13% | |
smooth muscle cell | 4 studies | 20% ± 4% | |
retinal ganglion cell | 3 studies | 56% ± 25% | |
ciliated cell | 3 studies | 27% ± 7% | |
macrophage | 3 studies | 17% ± 2% | |
GABAergic neuron | 3 studies | 29% ± 7% | |
glutamatergic neuron | 3 studies | 40% ± 8% | |
dendritic cell | 3 studies | 18% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 3968.38 | 258 / 258 | 100% | 35.77 | 230 / 230 |
brain | 100% | 3866.26 | 2642 / 2642 | 100% | 43.23 | 705 / 705 |
esophagus | 100% | 2490.36 | 1445 / 1445 | 100% | 12.46 | 183 / 183 |
kidney | 100% | 3685.47 | 89 / 89 | 100% | 28.31 | 901 / 901 |
liver | 100% | 2310.46 | 226 / 226 | 100% | 25.44 | 406 / 406 |
ovary | 100% | 1992.38 | 180 / 180 | 100% | 14.64 | 430 / 430 |
prostate | 100% | 2238.06 | 245 / 245 | 100% | 22.88 | 502 / 502 |
breast | 100% | 1972.75 | 459 / 459 | 100% | 23.40 | 1115 / 1118 |
thymus | 100% | 2502.21 | 653 / 653 | 100% | 28.85 | 603 / 605 |
stomach | 100% | 2024.05 | 359 / 359 | 100% | 15.07 | 285 / 286 |
lung | 99% | 1687.98 | 574 / 578 | 100% | 15.77 | 1154 / 1155 |
bladder | 100% | 2090.29 | 21 / 21 | 99% | 14.30 | 500 / 504 |
uterus | 100% | 1944.15 | 170 / 170 | 99% | 17.50 | 455 / 459 |
intestine | 100% | 2311.28 | 966 / 966 | 99% | 14.73 | 521 / 527 |
pancreas | 99% | 1062.03 | 326 / 328 | 99% | 13.99 | 176 / 178 |
skin | 95% | 1322.28 | 1717 / 1809 | 97% | 20.35 | 458 / 472 |
adipose | 100% | 1932.31 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2785.83 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.90 | 29 / 29 |
spleen | 100% | 1198.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.75 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.77 | 1 / 1 |
muscle | 100% | 2387.31 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 96% | 2802.63 | 830 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 73% | 6.57 | 58 / 80 |
peripheral blood | 24% | 244.04 | 227 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006777 | Biological process | Mo-molybdopterin cofactor biosynthetic process |
GO_0032324 | Biological process | molybdopterin cofactor biosynthetic process |
GO_1990140 | Cellular component | molybdopterin synthase complex |
GO_0016607 | Cellular component | nuclear speck |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0030366 | Molecular function | molybdopterin synthase activity |
GO_0005515 | Molecular function | protein binding |
GO_0000166 | Molecular function | nucleotide binding |
Gene name | MOCS2 |
Protein name | Molybdopterin synthase sulfur carrier subunit (MOCO1-A) (Molybdenum cofactor synthesis protein 2 small subunit) (Molybdenum cofactor synthesis protein 2A) (MOCS2A) (Molybdopterin-synthase small subunit) (Sulfur carrier protein MOCS2A) Molybdopterin synthase sulfur carrier subunit (Molybdenum cofactor synthesis protein 2 small subunit) (Molybdenum cofactor synthesis protein 2A) (MOCS2A) (Sulfur carrier protein MOCS2A) Molybdopterin synthase catalytic subunit (EC 2.8.1.12) (MOCO1-B) (Molybdenum cofactor synthesis protein 2 large subunit) (Molybdenum cofactor synthesis protein 2B) (MOCS2B) (Molybdopterin-synthase large subunit) (MPT synthase large subunit) |
Synonyms | MOCO1 MCBPE |
Description | FUNCTION: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. . FUNCTION: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. . FUNCTION: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. . |
Accessions | O96033 O96007 ENST00000582677.5 ENST00000527216.5 ENST00000450852.8 ENST00000396954.8 ENST00000508922.5 ENST00000510818.6 E9PKT9 ENST00000361377.8 ENST00000584946.5 |