I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 23% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 23% ± 8% |
Insufficient scRNA-seq data for expression of MMP15 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 5217.97 | 226 / 226 | 98% | 85.09 | 398 / 406 |
| pancreas | 99% | 2082.25 | 325 / 328 | 98% | 73.87 | 175 / 178 |
| intestine | 96% | 3903.56 | 931 / 966 | 98% | 105.22 | 517 / 527 |
| stomach | 94% | 4310.28 | 338 / 359 | 98% | 111.78 | 280 / 286 |
| thymus | 100% | 9824.92 | 653 / 653 | 87% | 126.27 | 524 / 605 |
| kidney | 100% | 2700.56 | 89 / 89 | 85% | 50.23 | 764 / 901 |
| bladder | 90% | 980.24 | 19 / 21 | 92% | 63.07 | 465 / 504 |
| lung | 93% | 1748.80 | 539 / 578 | 85% | 57.48 | 986 / 1155 |
| esophagus | 75% | 942.38 | 1086 / 1445 | 87% | 71.68 | 159 / 183 |
| breast | 83% | 1484.00 | 382 / 459 | 78% | 31.85 | 870 / 1118 |
| prostate | 75% | 820.99 | 183 / 245 | 80% | 24.21 | 402 / 502 |
| brain | 68% | 683.74 | 1805 / 2642 | 82% | 31.85 | 578 / 705 |
| adrenal gland | 60% | 588.16 | 156 / 258 | 86% | 56.48 | 197 / 230 |
| skin | 57% | 513.97 | 1024 / 1809 | 86% | 69.83 | 408 / 472 |
| uterus | 47% | 478.15 | 80 / 170 | 78% | 39.91 | 359 / 459 |
| ovary | 8% | 68.19 | 14 / 180 | 93% | 54.30 | 400 / 430 |
| ureter | 0% | 0 | 0 / 0 | 100% | 48.16 | 1 / 1 |
| heart | 99% | 4561.01 | 852 / 861 | 0% | 0 | 0 / 0 |
| spleen | 97% | 1810.52 | 234 / 241 | 0% | 0 | 0 / 0 |
| adipose | 88% | 1714.65 | 1058 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 60% | 16.55 | 48 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 18.08 | 23 / 45 |
| muscle | 34% | 310.44 | 270 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 17% | 188.62 | 226 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.87 | 1 / 29 |
| peripheral blood | 2% | 25.40 | 23 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032355 | Biological process | response to estradiol |
| GO_0035987 | Biological process | endodermal cell differentiation |
| GO_0030198 | Biological process | extracellular matrix organization |
| GO_0022617 | Biological process | extracellular matrix disassembly |
| GO_0030574 | Biological process | collagen catabolic process |
| GO_0036211 | Biological process | protein modification process |
| GO_0006508 | Biological process | proteolysis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0004222 | Molecular function | metalloendopeptidase activity |
| GO_0008047 | Molecular function | enzyme activator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0070006 | Molecular function | metalloaminopeptidase activity |
| Gene name | MMP15 |
| Protein name | Matrix metallopeptidase 15 Matrix metalloproteinase-15 (MMP-15) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP-2) |
| Synonyms | |
| Description | FUNCTION: Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. . |
| Accessions | P51511 ENST00000219271.4 H3BT97 ENST00000570065.1 |
