MKNK1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0018105Biological processpeptidyl-serine phosphorylation
GO_0035556Biological processintracellular signal transduction
GO_0006468Biological processprotein phosphorylation
GO_0046777Biological processprotein autophosphorylation
GO_0006417Biological processregulation of translation
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004683Molecular functioncalmodulin-dependent protein kinase activity
GO_0005516Molecular functioncalmodulin binding
GO_0009931Molecular functioncalcium-dependent protein serine/threonine kinase activity
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0106310Molecular functionprotein serine kinase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameMKNK1
Protein nameMAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
MAPK interacting serine/threonine kinase 1
MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1)
SynonymsDKFZp686E14208
MNK1
DescriptionFUNCTION: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

FUNCTION: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

FUNCTION: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

FUNCTION: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

FUNCTION: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

FUNCTION: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

FUNCTION: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

FUNCTION: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. .

AccessionsENST00000428112.7
E9PSE0
E9PII5
ENST00000496619.6
ENST00000371945.10
ENST00000650508.1 [Q9BUB5-2]
ENST00000341183.9
ENST00000650026.1 [Q9BUB5-3]
ENST00000531355.6
E9PN34
ENST00000524749.5
ENST00000532110.1
E9PMM8
ENST00000528077.6
A0A499FIS5
B5BUJ6
ENST00000465783.6
ENST00000531769.6
B5BU64
E9PIA0
Q9BUB5
ENST00000474868.2
ENST00000529170.6
E9PSC9
E9PLE7
ENST00000526513.6
E9PQ26
H0YE67
ENST00000371946.9
A0A499FJN1
ENST00000649800.1 [Q9BUB5-1]
Q7Z319
A0A499FJS1