Insufficient scRNA-seq data for expression of MINDY1 at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 3135.62 | 328 / 328 | 100% | 30.69 | 178 / 178 |
| kidney | 100% | 3253.03 | 89 / 89 | 99% | 33.03 | 890 / 901 |
| breast | 100% | 2043.13 | 457 / 459 | 99% | 65.11 | 1109 / 1118 |
| brain | 99% | 1552.58 | 2614 / 2642 | 100% | 41.96 | 702 / 705 |
| prostate | 100% | 1869.33 | 245 / 245 | 98% | 27.68 | 493 / 502 |
| intestine | 100% | 2169.00 | 965 / 966 | 97% | 21.37 | 513 / 527 |
| bladder | 100% | 1845.00 | 21 / 21 | 97% | 24.63 | 488 / 504 |
| stomach | 100% | 2447.91 | 359 / 359 | 96% | 20.75 | 275 / 286 |
| lung | 98% | 1584.96 | 568 / 578 | 97% | 21.84 | 1126 / 1155 |
| ovary | 100% | 2363.55 | 180 / 180 | 95% | 19.96 | 407 / 430 |
| thymus | 100% | 4790.92 | 653 / 653 | 95% | 43.95 | 572 / 605 |
| skin | 95% | 1764.26 | 1713 / 1809 | 99% | 34.24 | 466 / 472 |
| esophagus | 100% | 2716.61 | 1444 / 1445 | 93% | 20.21 | 171 / 183 |
| uterus | 100% | 2610.72 | 170 / 170 | 92% | 19.47 | 424 / 459 |
| liver | 93% | 1155.86 | 211 / 226 | 97% | 24.07 | 392 / 406 |
| adrenal gland | 97% | 1582.30 | 250 / 258 | 90% | 20.61 | 206 / 230 |
| eye | 0% | 0 | 0 / 0 | 100% | 25.28 | 80 / 80 |
| spleen | 100% | 1846.78 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 12.87 | 1 / 1 |
| blood vessel | 99% | 1581.67 | 1322 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 99% | 1672.66 | 1192 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1214.47 | 788 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 2692.87 | 841 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 3524.76 | 879 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 84% | 13.19 | 38 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 7.15 | 21 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0071108 | Biological process | protein K48-linked deubiquitination |
| GO_0006508 | Biological process | proteolysis |
| GO_0008150 | Biological process | biological_process |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0036435 | Molecular function | K48-linked polyubiquitin modification-dependent protein binding |
| GO_0016807 | Molecular function | cysteine-type carboxypeptidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_1990380 | Molecular function | K48-linked deubiquitinase activity |
| GO_0004843 | Molecular function | cysteine-type deubiquitinase activity |
| Gene name | MINDY1 |
| Protein name | Ubiquitin carboxyl-terminal hydrolase MINDY-1 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-1) (Protein FAM63A) MINDY lysine 48 deubiquitinase 1 |
| Synonyms | KIAA1390 FAM63A |
| Description | FUNCTION: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover. . |
| Accessions | ENST00000361936.9 [Q8N5J2-1] ENST00000683666.2 [Q8N5J2-1] ENST00000312210.9 [Q8N5J2-2] H0YJH5 ENST00000497067.1 ENST00000493834.2 [Q8N5J2-4] Q8N5J2 ENST00000361738.12 [Q8N5J2-1] |
