MIEF2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MIEF2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MIEF2 at tissue level.

III. Associated gene sets

GO_0007005Biological processmitochondrion organization
GO_0010821Biological processregulation of mitochondrion organization
GO_0090141Biological processpositive regulation of mitochondrial fission
GO_0008053Biological processmitochondrial fusion
GO_0090314Biological processpositive regulation of protein targeting to membrane
GO_0005741Cellular componentmitochondrial outer membrane
GO_0005777Cellular componentperoxisome
GO_0005739Cellular componentmitochondrion
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMIEF2
Protein nameMitochondrial dynamics protein MID49 (Mitochondrial dynamics protein of 49 kDa) (Mitochondrial elongation factor 2) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein)
Mitochondrial dynamics protein MID49 (Mitochondrial elongation factor 2)
SynonymsSMCR7
MID49
DescriptionFUNCTION: Mitochondrial outer membrane protein involved in the regulation of mitochondrial organization . It is required for mitochondrial fission and promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity. .

AccessionsENST00000640642.1
ENST00000640122.2 [Q96C03-1]
J3QR30
A8MT25
ENST00000395706.2 [Q96C03-3]
Q96C03
ENST00000639927.1
K7EKV6
ENST00000578621.5
ENST00000640637.1 [Q96C03-2]
ENST00000578174.5
ENST00000640339.1 [Q96C03-3]
ENST00000638355.1
J3KTJ4
ENST00000395704.8 [Q96C03-2]
ENST00000323019.9 [Q96C03-1]
ENST00000579341.5
ENST00000639502.1
ENST00000395703.8