MGAT5B | OmnibusX

Name	Number of supported studies	Average coverage
brain	5 studies	29% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	96%	4601.19	2542 / 2642	98%	16.58	693 / 705
eye	0%	0	0 / 0	100%	36.64	80 / 80
skin	1%	2.00	14 / 1809	86%	17.06	404 / 472
lung	34%	104.99	196 / 578	22%	0.91	256 / 1155
uterus	20%	51.92	34 / 170	34%	1.36	156 / 459
adrenal gland	3%	10.04	8 / 258	39%	2.10	89 / 230
ovary	4%	7.23	7 / 180	37%	2.57	158 / 430
breast	7%	16.88	34 / 459	29%	1.64	328 / 1118
prostate	1%	1.55	2 / 245	28%	0.71	143 / 502
tonsil	0%	0	0 / 0	27%	0.77	12 / 45
thymus	17%	42.28	108 / 653	8%	0.23	49 / 605
esophagus	4%	9.56	55 / 1445	20%	0.66	36 / 183
kidney	15%	32.69	13 / 89	7%	0.21	60 / 901
pancreas	0%	0	0 / 328	21%	0.87	37 / 178
spleen	15%	35.67	36 / 241	0%	0	0 / 0
bladder	0%	0	0 / 21	12%	0.38	59 / 504
stomach	2%	4.13	7 / 359	8%	0.30	23 / 286
intestine	4%	8.49	35 / 966	6%	0.25	29 / 527
adipose	6%	17.47	78 / 1204	0%	0	0 / 0
blood vessel	2%	6.14	31 / 1335	0%	0	0 / 0
liver	0%	0	0 / 226	2%	0.17	8 / 406
heart	0%	0.61	2 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006487	Biological process	protein N-linked glycosylation
GO_0018242	Biological process	protein O-linked glycosylation via serine
GO_0000139	Cellular component	Golgi membrane
GO_0005794	Cellular component	Golgi apparatus
GO_0030145	Molecular function	manganese ion binding
GO_0030144	Molecular function	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
GO_0005515	Molecular function	protein binding

Gene name	MGAT5B
Protein name	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.-) (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B) (GlcNAc-T Vb) (GNT-Vb) (hGnTVb) (Mannoside acetylglucosaminyltransferase 5B) (N-acetylglucosaminyl-transferase Vb) (N-acetylglucosaminyltransferase IX) (GNT-IX) Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase (EC 2.4.1.155)
Synonyms	KIAA2008
Description	FUNCTION: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. .
Accessions	Q3V5L5 ENST00000565675.1 H3BR20 ENST00000428789.6 [Q3V5L5-2] H3BQ65 ENST00000301618.8 [Q3V5L5-5] ENST00000565043.5 ENST00000569840.7 [Q3V5L5-1]

MGAT5B report