MGAT4C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006487Biological processprotein N-linked glycosylation
GO_0019082Biological processviral protein processing
GO_0000139Cellular componentGolgi membrane
GO_0008375Molecular functionacetylglucosaminyltransferase activity
GO_0008454Molecular functionalpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameMGAT4C
Protein nameAlpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc)
MGAT4 family member C
Synonyms
DescriptionFUNCTION: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). .

AccessionsENST00000552435.6
ENST00000620241.5 [Q9UBM8-1]
ENST00000552808.7 [Q9UBM8-1]
Q9UBM8
ENST00000548651.6 [Q9UBM8-1]
ENST00000547225.5
F8VTY5
ENST00000611864.5 [Q9UBM8-1]
F8VWY2
ENST00000621808.5 [Q9UBM8-1]