MGARP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008089Biological processanterograde axonal transport
GO_0097211Biological processcellular response to gonadotropin-releasing hormone
GO_0071383Biological processcellular response to steroid hormone stimulus
GO_0021987Biological processcerebral cortex development
GO_0010821Biological processregulation of mitochondrion organization
GO_0006626Biological processprotein targeting to mitochondrion
GO_0061564Biological processaxon development
GO_0019896Biological processaxonal transport of mitochondrion
GO_2000171Biological processnegative regulation of dendrite development
GO_0008090Biological processretrograde axonal transport
GO_0071456Biological processcellular response to hypoxia
GO_0005741Cellular componentmitochondrial outer membrane
GO_1904115Cellular componentaxon cytoplasm
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMGARP
Protein nameProtein MGARP (Corneal endothelium-specific protein 1) (CESP-1) (Hypoxia up-regulated mitochondrial movement regulator protein) (Mitochondria-localized glutamic acid-rich protein) (Ovary-specific acidic protein)
SynonymsC4orf49
OSAP
HUMMR
GS3582
CESP1
DescriptionFUNCTION: Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity). Plays an inhibitory role during neocortex development by regulating mitochondrial morphology, distribution and motility in neocortical neurons (By similarity). .

AccessionsQ8TDB4
ENST00000398955.2