MGAM report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MGAM at tissue level.

III. Associated gene sets

GO_0005983Biological processstarch catabolic process
GO_0000025Biological processmaltose catabolic process
GO_1901027Biological processdextrin catabolic process
GO_0016324Cellular componentapical plasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0070821Cellular componenttertiary granule membrane
GO_0005886Cellular componentplasma membrane
GO_0101003Cellular componentficolin-1-rich granule membrane
GO_0004558Molecular functionalpha-1,4-glucosidase activity
GO_0004339Molecular functionglucan 1,4-alpha-glucosidase activity
GO_0003824Molecular functioncatalytic activity
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding
GO_0032450Molecular functionmaltose alpha-glucosidase activity
GO_0016160Molecular functionamylase activity

IV. Literature review

[source]
Gene nameMGAM
Protein nameMaltase-glucoamylase
Maltase-glucoamylase (Alpha-1,4-glucosidase) (EC 3.2.1.20)
SynonymsMGAML
MGA
DescriptionFUNCTION: Alpha-(1,4) exo-glucosidase involved in breakdown of dietary starch oligosaccharides in small intestine. Cleaves the non-reducing alpha-(1,4)-linked glucose residue in linear dextrins with retention of anomeric center stereochemistry . Mainly hydrolyzes short length oligomaltoses having two to seven glucose residues . Can cleave alpha-(1,2), alpha-(1,3) and alpha-(1,6) glycosidic linkages with lower efficiency, whereas beta glycosidic linkages are usually not hydrolyzed . .

AccessionsE9PEQ5
ENST00000632195.1
A0A0J9YX77
Q8TE25
A0A0J9YVZ3
ENST00000497673.5
ENST00000631981.1
ENST00000465654.5
E7EW87
O43451
ENST00000549489.6 [O43451-1]
ENST00000475668.6 [O43451-2]
Q8TE24
ENST00000620571.1 [O43451-1]