Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 8 studies | 28% ± 10% | |
GABAergic neuron | 7 studies | 43% ± 19% | |
endothelial cell | 6 studies | 28% ± 11% | |
glutamatergic neuron | 6 studies | 44% ± 25% | |
epithelial cell | 5 studies | 37% ± 15% | |
ciliated cell | 5 studies | 24% ± 8% | |
astrocyte | 5 studies | 29% ± 9% | |
oligodendrocyte precursor cell | 5 studies | 32% ± 12% | |
interneuron | 5 studies | 44% ± 22% | |
fibroblast | 4 studies | 20% ± 6% | |
neuron | 3 studies | 26% ± 10% | |
GABAergic interneuron | 3 studies | 24% ± 4% | |
microglial cell | 3 studies | 21% ± 2% | |
cardiac muscle cell | 3 studies | 16% ± 0% | |
macrophage | 3 studies | 19% ± 4% | |
basal cell | 3 studies | 26% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2871.52 | 21 / 21 | 100% | 26.86 | 504 / 504 |
esophagus | 100% | 3284.40 | 1445 / 1445 | 100% | 39.26 | 183 / 183 |
ovary | 100% | 2889.81 | 180 / 180 | 100% | 31.17 | 430 / 430 |
lung | 100% | 2671.81 | 578 / 578 | 100% | 37.28 | 1153 / 1155 |
breast | 100% | 3007.03 | 459 / 459 | 100% | 36.30 | 1116 / 1118 |
uterus | 100% | 3407.34 | 170 / 170 | 100% | 34.66 | 458 / 459 |
stomach | 100% | 2805.21 | 359 / 359 | 100% | 24.84 | 285 / 286 |
prostate | 100% | 3148.27 | 245 / 245 | 100% | 34.04 | 500 / 502 |
pancreas | 100% | 3048.08 | 328 / 328 | 99% | 22.60 | 177 / 178 |
thymus | 100% | 2613.52 | 653 / 653 | 99% | 19.11 | 599 / 605 |
intestine | 100% | 3167.98 | 966 / 966 | 99% | 23.01 | 521 / 527 |
brain | 99% | 2039.39 | 2604 / 2642 | 100% | 22.16 | 705 / 705 |
kidney | 100% | 2198.27 | 89 / 89 | 99% | 19.63 | 888 / 901 |
skin | 100% | 3532.65 | 1809 / 1809 | 94% | 26.85 | 443 / 472 |
adrenal gland | 100% | 2932.61 | 258 / 258 | 89% | 10.38 | 205 / 230 |
liver | 100% | 1262.23 | 226 / 226 | 88% | 11.19 | 358 / 406 |
adipose | 100% | 2772.19 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3138.57 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 23.73 | 29 / 29 |
spleen | 100% | 3633.09 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 39.97 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.79 | 1 / 1 |
muscle | 100% | 2316.98 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 2961.95 | 847 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 73% | 2509.81 | 679 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 56% | 6.72 | 45 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0046039 | Biological process | GTP metabolic process |
GO_0008053 | Biological process | mitochondrial fusion |
GO_0010918 | Biological process | positive regulation of mitochondrial membrane potential |
GO_0051646 | Biological process | mitochondrion localization |
GO_0005741 | Cellular component | mitochondrial outer membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0016020 | Cellular component | membrane |
GO_0098799 | Cellular component | outer mitochondrial membrane protein complex |
GO_0005525 | Molecular function | GTP binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | MFN1 |
Protein name | Mitofusin 1 MFN1 protein Mitofusin-1 (EC 3.6.5.-) (Fzo homolog) (Transmembrane GTPase MFN1) |
Synonyms | |
Description | FUNCTION: Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion . Membrane clustering requires GTPase activity . It may involve a major rearrangement of the coiled coil domains . Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events . Overexpression induces the formation of mitochondrial networks (in vitro) . Has low GTPase activity . . |
Accessions | H7C5H5 C9JXQ1 ENST00000489329.5 ENST00000467174.6 Q8IWA4 ENST00000357390.8 [Q8IWA4-2] Q05CV7 C9JQT7 ENST00000471841.6 [Q8IWA4-1] ENST00000263969.9 [Q8IWA4-1] ENST00000474903.1 |