Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 7 studies | 34% ± 18% | |
| glutamatergic neuron | 5 studies | 44% ± 21% | |
| interneuron | 5 studies | 36% ± 23% | |
| astrocyte | 4 studies | 24% ± 5% | |
| oligodendrocyte | 4 studies | 20% ± 2% | |
| oligodendrocyte precursor cell | 3 studies | 26% ± 5% | |
| neuron | 3 studies | 24% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 35% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 795.70 | 2642 / 2642 | 100% | 12.68 | 705 / 705 |
| breast | 100% | 438.25 | 459 / 459 | 100% | 9.43 | 1118 / 1118 |
| uterus | 100% | 513.17 | 170 / 170 | 100% | 7.59 | 458 / 459 |
| ovary | 100% | 573.34 | 180 / 180 | 100% | 6.79 | 429 / 430 |
| bladder | 100% | 444.95 | 21 / 21 | 100% | 7.16 | 502 / 504 |
| prostate | 100% | 507.66 | 245 / 245 | 100% | 8.12 | 500 / 502 |
| thymus | 100% | 469.05 | 653 / 653 | 99% | 6.77 | 601 / 605 |
| skin | 100% | 528.17 | 1808 / 1809 | 99% | 8.71 | 465 / 472 |
| lung | 98% | 374.15 | 566 / 578 | 99% | 5.96 | 1148 / 1155 |
| kidney | 100% | 404.58 | 89 / 89 | 97% | 4.90 | 876 / 901 |
| pancreas | 98% | 218.02 | 322 / 328 | 99% | 5.91 | 176 / 178 |
| intestine | 100% | 406.67 | 966 / 966 | 97% | 5.04 | 511 / 527 |
| stomach | 100% | 318.62 | 359 / 359 | 97% | 4.74 | 276 / 286 |
| adrenal gland | 100% | 445.47 | 258 / 258 | 96% | 5.99 | 221 / 230 |
| esophagus | 100% | 361.48 | 1443 / 1445 | 95% | 4.04 | 174 / 183 |
| liver | 100% | 297.49 | 226 / 226 | 91% | 3.92 | 370 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 8.61 | 29 / 29 |
| spleen | 100% | 517.14 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 6.44 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.54 | 1 / 1 |
| adipose | 100% | 430.02 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 385.26 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 310.80 | 795 / 803 | 0% | 0 | 0 / 0 |
| heart | 93% | 239.38 | 805 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 88% | 3.82 | 70 / 80 |
| peripheral blood | 81% | 293.77 | 751 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030488 | Biological process | tRNA methylation |
| GO_0006400 | Biological process | tRNA modification |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0052735 | Molecular function | tRNA (cytidine-3-)-methyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | METTL6 |
| Protein name | Methyltransferase 6, methylcytidine tRNA N(3)-methylcytidine methyltransferase METTL6 (EC 2.1.1.-) (Methyltransferase-like protein 6) (hMETTL6) Methyltransferase 6, methylcytidine (cDNA FLJ57901, highly similar to Methyltransferase-like protein 6) |
| Synonyms | |
| Description | FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser), including tRNA(Ser)(UGA) and tRNA(Ser)(GCU) . Interaction with SARS1/SerRS is required for N(3)-methylcytidine methylation . . |
| Accessions | ENST00000443029.5 [Q8TCB7-1] H7C1L4 ENST00000383789.9 [Q8TCB7-2] Q8TCB7 ENST00000458728.5 B4DDX3 H7C3H9 M0R0W0 ENST00000598878.1 ENST00000453819.5 ENST00000383790.8 [Q8TCB7-1] ENST00000450816.6 |
