METTL2A | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	24% ± 7%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of METTL2A at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	536.93	459 / 459	100%	15.91	1118 / 1118
esophagus	100%	585.24	1445 / 1445	100%	10.87	183 / 183
liver	100%	456.90	226 / 226	100%	7.65	406 / 406
ovary	100%	469.88	180 / 180	100%	10.91	430 / 430
pancreas	100%	390.17	328 / 328	100%	8.50	178 / 178
prostate	100%	521.48	245 / 245	100%	10.93	502 / 502
stomach	100%	496.59	359 / 359	100%	11.43	286 / 286
brain	100%	521.06	2640 / 2642	100%	17.26	705 / 705
lung	100%	497.74	577 / 578	100%	12.54	1155 / 1155
intestine	100%	598.38	966 / 966	100%	11.79	526 / 527
bladder	100%	532.81	21 / 21	100%	12.35	503 / 504
uterus	100%	518.72	170 / 170	100%	12.62	458 / 459
thymus	100%	500.35	653 / 653	100%	9.16	603 / 605
kidney	100%	484.57	89 / 89	100%	9.19	898 / 901
skin	100%	746.52	1809 / 1809	100%	11.89	470 / 472
adrenal gland	100%	709.87	258 / 258	98%	7.63	226 / 230
adipose	100%	523.74	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	10.33	29 / 29
spleen	100%	466.20	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	12.19	45 / 45
ureter	0%	0	0 / 0	100%	8.08	1 / 1
blood vessel	100%	483.64	1334 / 1335	0%	0	0 / 0
muscle	100%	504.35	802 / 803	0%	0	0 / 0
heart	99%	503.50	851 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	7.16	76 / 80
peripheral blood	75%	375.53	701 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

Gene name	METTL2A
Protein name	tRNA N(3)-methylcytidine methyltransferase (EC 2.1.1.-) tRNA N(3)-methylcytidine methyltransferase METTL2A (EC 2.1.1.-) (Methyltransferase-like protein 2A)
Synonyms	HSPC266 METTL2
Description	FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU) . N(3)-methylcytidine methylation by METTL2A requires the N6-threonylcarbamoylation of tRNA (t6A37) by the EKC/KEOPS complex as prerequisite . . FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase. .
Accessions	ENST00000311506.10 [Q96IZ6-1] Q96IZ6 ENST00000616852.1 A0A087WW35

GO_0006399	Biological process	tRNA metabolic process
GO_0006400	Biological process	tRNA modification
GO_0030488	Biological process	tRNA methylation
GO_0005737	Cellular component	cytoplasm
GO_0052735	Molecular function	tRNA (cytidine-3-)-methyltransferase activity
GO_0005515	Molecular function	protein binding

METTL2A report