I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 16% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 16% ± 1% |
Insufficient scRNA-seq data for expression of METTL22 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 1277.19 | 21 / 21 | 100% | 5.69 | 504 / 504 |
| breast | 100% | 1143.09 | 459 / 459 | 100% | 5.26 | 1118 / 1118 |
| esophagus | 100% | 1145.15 | 1445 / 1445 | 100% | 5.30 | 183 / 183 |
| intestine | 100% | 1209.34 | 966 / 966 | 100% | 4.83 | 527 / 527 |
| ovary | 100% | 1383.18 | 180 / 180 | 100% | 5.31 | 430 / 430 |
| pancreas | 100% | 673.55 | 328 / 328 | 100% | 4.58 | 178 / 178 |
| prostate | 100% | 1371.64 | 245 / 245 | 100% | 5.56 | 502 / 502 |
| stomach | 100% | 920.93 | 359 / 359 | 100% | 4.73 | 286 / 286 |
| uterus | 100% | 1655.89 | 170 / 170 | 100% | 6.29 | 459 / 459 |
| skin | 100% | 1082.23 | 1808 / 1809 | 100% | 5.24 | 472 / 472 |
| lung | 100% | 1058.29 | 577 / 578 | 100% | 5.39 | 1155 / 1155 |
| liver | 100% | 627.31 | 226 / 226 | 100% | 3.08 | 405 / 406 |
| thymus | 100% | 1045.39 | 653 / 653 | 100% | 4.33 | 603 / 605 |
| kidney | 100% | 789.88 | 89 / 89 | 99% | 4.49 | 896 / 901 |
| adrenal gland | 100% | 940.93 | 258 / 258 | 99% | 5.69 | 227 / 230 |
| brain | 97% | 800.02 | 2560 / 2642 | 100% | 5.68 | 705 / 705 |
| adipose | 100% | 1013.71 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1132.32 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 5.34 | 29 / 29 |
| muscle | 100% | 2485.77 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1004.39 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 4.89 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.68 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 4.79 | 79 / 80 |
| peripheral blood | 99% | 862.98 | 917 / 929 | 0% | 0 | 0 / 0 |
| heart | 98% | 1059.00 | 846 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006479 | Biological process | protein methylation |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0005730 | Cellular component | nucleolus |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0008276 | Molecular function | protein methyltransferase activity |
| GO_0042054 | Molecular function | histone methyltransferase activity |
| GO_0031072 | Molecular function | heat shock protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016279 | Molecular function | protein-lysine N-methyltransferase activity |
| Gene name | METTL22 |
| Protein name | Methyltransferase-like protein 22 (EC 2.1.1.-) Methyltransferase 22, Kin17 lysine |
| Synonyms | C16orf68 LP8272 |
| Description | FUNCTION: Protein N-lysine methyltransferase. Trimethylates KIN at Lys-135 (in vitro). . |
| Accessions | H3BTR2 H3BSA9 ENST00000564554.1 ENST00000562973.1 ENST00000562151.2 H3BTF5 ENST00000567295.5 I3L3I8 H3BV20 ENST00000381920.8 [Q9BUU2-1] ENST00000572956.5 Q9BUU2 ENST00000563958.5 I3L2J5 H3BTI6 I3L483 ENST00000561758.5 ENST00000163678.11 [Q9BUU2-2] ENST00000565866.5 |
