METAP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070527Biological processplatelet aggregation
GO_0051604Biological processprotein maturation
GO_0031365Biological processN-terminal protein amino acid modification
GO_0018206Biological processpeptidyl-methionine modification
GO_0006508Biological processproteolysis
GO_0006417Biological processregulation of translation
GO_0022626Cellular componentcytosolic ribosome
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0004239Molecular functioninitiator methionyl aminopeptidase activity
GO_0008235Molecular functionmetalloexopeptidase activity
GO_0005515Molecular functionprotein binding
GO_0070006Molecular functionmetalloaminopeptidase activity
GO_0046872Molecular functionmetal ion binding
GO_0004177Molecular functionaminopeptidase activity

IV. Literature review

[source]
Gene nameMETAP1
Protein nameMethionyl aminopeptidase 1
Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1)
SynonymsKIAA0094
DescriptionFUNCTION: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle. .

AccessionsENST00000514051.1
ENST00000510133.5
ENST00000506238.5
P53582
H0Y9L0
H0Y903
D6RF24
H0YAI3
H0Y955
ENST00000503247.5
ENST00000507537.5
ENST00000296411.11
ENST00000510107.5
ENST00000625963.1