MEPE report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MEPE at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MEPE at tissue level.

III. Associated gene sets

GO_0001501Biological processskeletal system development
GO_0031214Biological processbiomineral tissue development
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0005576Cellular componentextracellular region
GO_0031012Cellular componentextracellular matrix
GO_0005201Molecular functionextracellular matrix structural constituent
GO_1990430Molecular functionextracellular matrix protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMEPE
Protein nameMatrix extracellular phosphoglycoprotein
Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45) (Osteoregulin)
Synonyms
DescriptionFUNCTION: Promotes renal phosphate excretion and inhibits intestinal phosphate absorption . Promotes bone mineralization by osteoblasts and cartilage mineralization by chondrocytes . Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage (By similarity). Promotes dental pulp stem cell proliferation and differentiation . .

AccessionsD6RFW6
ENST00000395102.8 [Q9NQ76-2]
A0A8I5QJK1
ENST00000424957.8 [Q9NQ76-1]
ENST00000560249.6
ENST00000497649.6
ENST00000515821.5
A0A8J9B5S1
Q9NQ76
D6C6M7
ENST00000511670.5
ENST00000361056.4 [Q9NQ76-1]
D6RAC8