Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 4 studies | 53% ± 23% | |
| astrocyte | 4 studies | 38% ± 15% | |
| glutamatergic neuron | 4 studies | 59% ± 27% | |
| oligodendrocyte | 3 studies | 34% ± 11% | |
| dendritic cell | 3 studies | 23% ± 4% | |
| interneuron | 3 studies | 43% ± 19% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 64% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 274.33 | 180 / 180 | 100% | 3.07 | 430 / 430 |
| esophagus | 100% | 221.27 | 1445 / 1445 | 99% | 3.20 | 182 / 183 |
| brain | 100% | 231.12 | 2640 / 2642 | 99% | 2.44 | 700 / 705 |
| prostate | 100% | 254.84 | 245 / 245 | 97% | 1.95 | 488 / 502 |
| stomach | 100% | 150.71 | 359 / 359 | 88% | 2.10 | 251 / 286 |
| bladder | 100% | 228.71 | 21 / 21 | 83% | 1.67 | 418 / 504 |
| thymus | 100% | 223.07 | 653 / 653 | 81% | 1.32 | 489 / 605 |
| lung | 100% | 175.01 | 576 / 578 | 78% | 1.63 | 904 / 1155 |
| uterus | 100% | 265.57 | 170 / 170 | 77% | 1.40 | 355 / 459 |
| breast | 100% | 192.25 | 459 / 459 | 73% | 1.27 | 818 / 1118 |
| intestine | 100% | 195.55 | 966 / 966 | 73% | 1.28 | 384 / 527 |
| skin | 100% | 200.99 | 1808 / 1809 | 65% | 1.03 | 307 / 472 |
| adrenal gland | 100% | 212.47 | 258 / 258 | 59% | 0.86 | 136 / 230 |
| pancreas | 99% | 106.61 | 325 / 328 | 54% | 1.06 | 97 / 178 |
| kidney | 100% | 140.62 | 89 / 89 | 38% | 0.58 | 338 / 901 |
| liver | 100% | 131.20 | 226 / 226 | 27% | 0.37 | 110 / 406 |
| adipose | 100% | 184.74 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 351.78 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 202.41 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.13 | 1 / 1 |
| blood vessel | 100% | 208.19 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 166.33 | 838 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 94% | 181.85 | 877 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 66% | 1.01 | 19 / 29 |
| eye | 0% | 0 | 0 / 0 | 26% | 0.39 | 21 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 0.33 | 11 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032886 | Biological process | regulation of microtubule-based process |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MEMO1 |
| Protein name | Protein MEMO1 (C21orf19-like protein) (Hepatitis C virus NS5A-transactivated protein 7) (HCV NS5A-transactivated protein 7) (Mediator of ErbB2-driven cell motility 1) (Mediator of cell motility 1) (Memo-1) Protein MEMO1 (Mediator of ErbB2-driven cell motility 1) Mediator of cell motility 1 |
| Synonyms | MEMO CGI-27 C2orf4 NS5ATP7 |
| Description | FUNCTION: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. . |
| Accessions | B5MCI6 ENST00000295065.9 [Q9Y316-1] C9JSD7 ENST00000437854.1 Q9Y316 ENST00000404530.6 [Q9Y316-1] ENST00000379383.7 [Q9Y316-3] ENST00000426310.6 [Q9Y316-2] ENST00000407893.3 |
