MEIOSIN report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MEIOSIN at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MEIOSIN at tissue level.

III. Associated gene sets

GO_0071300Biological processcellular response to retinoic acid
GO_0051321Biological processmeiotic cell cycle
GO_0007283Biological processspermatogenesis
GO_0048477Biological processoogenesis
GO_0090427Biological processactivation of meiosis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0046983Molecular functionprotein dimerization activity

IV. Literature review

[source]
Gene nameMEIOSIN
Protein nameMeiosis initiator protein (Basic helix-loop-helix and HMG box domain-containing protein 1)
SynonymsBHMG1
DescriptionFUNCTION: Gatekeeper of meiotic initiation in both male and female germ cells. In complex with STRA8, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis. Temporal expression of MEIOSIN is required for meiotic entry decision. .

AccessionsENST00000457052.3
C9JSJ3