MEI4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MEI4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MEI4 at tissue level.

III. Associated gene sets

GO_0006310Biological processDNA recombination
GO_0007283Biological processspermatogenesis
GO_0042138Biological processmeiotic DNA double-strand break formation
GO_0048477Biological processoogenesis
GO_0007129Biological processhomologous chromosome pairing at meiosis
GO_0000800Cellular componentlateral element
GO_0005694Cellular componentchromosome
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMEI4
Protein nameMeiosis-specific protein MEI4
Synonyms
DescriptionFUNCTION: Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with IHO1 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. .

AccessionsA8MW99
ENST00000684080.1
ENST00000649759.1
ENST00000602452.3