I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 28% ± 9% | |
| retinal cone cell | 3 studies | 20% ± 3% | |
| GABAergic neuron | 3 studies | 26% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 28% ± 9% | |
| retinal cone cell | 3 studies | 20% ± 3% | |
| GABAergic neuron | 3 studies | 26% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 20% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 879.53 | 966 / 966 | 100% | 7.61 | 526 / 527 |
| bladder | 100% | 1138.62 | 21 / 21 | 100% | 13.92 | 502 / 504 |
| uterus | 100% | 999.99 | 170 / 170 | 99% | 15.26 | 456 / 459 |
| breast | 100% | 904.11 | 459 / 459 | 99% | 10.98 | 1110 / 1118 |
| prostate | 100% | 888.52 | 245 / 245 | 99% | 5.80 | 497 / 502 |
| esophagus | 100% | 1521.14 | 1445 / 1445 | 99% | 11.44 | 181 / 183 |
| skin | 100% | 1370.76 | 1809 / 1809 | 99% | 7.84 | 466 / 472 |
| lung | 99% | 615.38 | 575 / 578 | 99% | 9.70 | 1146 / 1155 |
| thymus | 100% | 854.31 | 653 / 653 | 99% | 5.82 | 596 / 605 |
| brain | 99% | 435.96 | 2613 / 2642 | 100% | 4.89 | 702 / 705 |
| kidney | 100% | 816.07 | 89 / 89 | 98% | 9.81 | 887 / 901 |
| pancreas | 99% | 341.77 | 325 / 328 | 99% | 10.07 | 176 / 178 |
| stomach | 100% | 652.85 | 359 / 359 | 98% | 6.58 | 280 / 286 |
| ovary | 100% | 941.32 | 180 / 180 | 93% | 4.59 | 401 / 430 |
| adrenal gland | 98% | 524.76 | 254 / 258 | 92% | 4.56 | 212 / 230 |
| adipose | 100% | 687.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 751.42 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 614.28 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 14.48 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.85 | 1 / 1 |
| liver | 67% | 158.49 | 151 / 226 | 32% | 1.54 | 128 / 406 |
| heart | 97% | 338.27 | 831 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 4.84 | 76 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 5.29 | 27 / 29 |
| muscle | 91% | 235.52 | 730 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 65% | 297.20 | 602 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0031929 | Biological process | TOR signaling |
| GO_0031667 | Biological process | response to nutrient levels |
| GO_0032868 | Biological process | response to insulin |
| GO_0043200 | Biological process | response to amino acid |
| GO_0030334 | Biological process | regulation of cell migration |
| GO_0150032 | Biological process | positive regulation of protein localization to lysosome |
| GO_0042127 | Biological process | regulation of cell population proliferation |
| GO_1900408 | Biological process | negative regulation of cellular response to oxidative stress |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MEAK7 |
| Protein name | MTOR associated protein, eak-7 homolog MTOR-associated protein MEAK7 (MEAK7) (MTOR associated protein, eak-7 homolog) (TBC/LysM-associated domain-containing protein 1) (TLD domain-containing protein 1) |
| Synonyms | KIAA1609 TLDC1 |
| Description | FUNCTION: Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration . Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome . . |
| Accessions | ENST00000570036.5 H3BTC5 ENST00000343629.11 H3BQ13 ENST00000566995.5 ENST00000562447.5 ENST00000565079.5 Q6P9B6 H3BPI4 ENST00000565765.1 H3BUB0 H3BM75 |
