Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 10 studies | 46% ± 24% | |
endothelial cell | 9 studies | 26% ± 13% | |
oligodendrocyte precursor cell | 9 studies | 26% ± 11% | |
GABAergic neuron | 8 studies | 48% ± 22% | |
adipocyte | 8 studies | 30% ± 8% | |
interneuron | 6 studies | 41% ± 16% | |
neuron | 4 studies | 28% ± 4% | |
epithelial cell | 4 studies | 19% ± 3% | |
granule cell | 4 studies | 25% ± 7% | |
cardiac muscle cell | 4 studies | 21% ± 2% | |
retina horizontal cell | 4 studies | 26% ± 7% | |
astrocyte | 4 studies | 32% ± 14% | |
endothelial cell of lymphatic vessel | 4 studies | 19% ± 1% | |
GABAergic interneuron | 3 studies | 43% ± 6% | |
ciliated cell | 3 studies | 22% ± 2% | |
pericyte | 3 studies | 18% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 2487.09 | 89 / 89 | 100% | 18.62 | 898 / 901 |
adrenal gland | 100% | 3159.24 | 258 / 258 | 100% | 20.43 | 229 / 230 |
thymus | 100% | 2017.01 | 653 / 653 | 99% | 17.16 | 599 / 605 |
pancreas | 100% | 1206.12 | 328 / 328 | 99% | 15.35 | 176 / 178 |
brain | 99% | 2176.71 | 2604 / 2642 | 100% | 22.33 | 704 / 705 |
intestine | 100% | 1977.37 | 966 / 966 | 97% | 16.86 | 513 / 527 |
ovary | 100% | 3815.92 | 180 / 180 | 96% | 12.19 | 412 / 430 |
prostate | 100% | 3086.04 | 245 / 245 | 95% | 18.53 | 478 / 502 |
stomach | 100% | 2155.87 | 359 / 359 | 94% | 14.74 | 269 / 286 |
bladder | 100% | 2424.19 | 21 / 21 | 92% | 16.36 | 463 / 504 |
breast | 100% | 2924.96 | 459 / 459 | 87% | 11.83 | 972 / 1118 |
lung | 100% | 1668.31 | 577 / 578 | 80% | 9.57 | 927 / 1155 |
uterus | 99% | 2968.31 | 169 / 170 | 80% | 10.36 | 366 / 459 |
esophagus | 89% | 1153.66 | 1290 / 1445 | 56% | 4.57 | 103 / 183 |
liver | 76% | 419.17 | 172 / 226 | 58% | 4.81 | 234 / 406 |
skin | 80% | 623.50 | 1456 / 1809 | 31% | 3.61 | 146 / 472 |
adipose | 100% | 2482.01 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1591.78 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 59.33 | 1 / 1 |
blood vessel | 100% | 1873.43 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 1731.83 | 852 / 861 | 0% | 0 | 0 / 0 |
muscle | 98% | 1021.14 | 789 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 40% | 3.49 | 32 / 80 |
tonsil | 0% | 0 | 0 / 0 | 40% | 2.99 | 18 / 45 |
lymph node | 0% | 0 | 0 / 0 | 28% | 1.19 | 8 / 29 |
peripheral blood | 2% | 8.14 | 14 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0072592 | Biological process | oxygen metabolic process |
GO_0006108 | Biological process | malate metabolic process |
GO_0009060 | Biological process | aerobic respiration |
GO_0006090 | Biological process | pyruvate metabolic process |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0004470 | Molecular function | malic enzyme activity |
GO_0051287 | Molecular function | NAD binding |
GO_0004473 | Molecular function | malate dehydrogenase (decarboxylating) (NADP+) activity |
GO_0008948 | Molecular function | oxaloacetate decarboxylase activity |
GO_0070401 | Molecular function | NADP+ binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | ME3 |
Protein name | Malic enzyme 3 Cadherin NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3) Malic enzyme Alternative protein ME3 |
Synonyms | |
Description | FUNCTION: Catalyzes the oxidative decarboxylation of (S)-malate to pyruvate using NADP(+) as a cofactor . Can also reverse the decarboxylation reaction, but only with significantly lower efficiency . . |
Accessions | E9PND9 ENST00000526834.1 ENST00000526504.5 [Q16798-2] ENST00000530335.1 L8ECD3 Q16798 ENST00000393324.7 [Q16798-1] ENST00000543262.6 [Q16798-1] E9PKA0 ENST00000323418.10 E9PNN2 ENST00000524826 ENST00000526944.1 O15201 Q6TCH8 ENST00000532471.1 ENST00000524826.8 [Q16798-1] E9PMB9 |