MCM10 | OmnibusX

Name	Number of supported studies	Average coverage
transit amplifying cell	3 studies	22% ± 7%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of MCM10 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	92%	190.95	420 / 459	85%	9.76	955 / 1118
skin	86%	423.24	1558 / 1809	87%	7.21	410 / 472
lung	67%	67.46	385 / 578	85%	8.36	984 / 1155
intestine	54%	79.46	519 / 966	94%	8.38	494 / 527
esophagus	47%	141.05	679 / 1445	97%	11.12	177 / 183
stomach	43%	58.58	155 / 359	93%	8.29	267 / 286
ovary	39%	28.06	71 / 180	91%	6.93	393 / 430
bladder	33%	22.00	7 / 21	92%	9.77	463 / 504
uterus	14%	10.81	23 / 170	97%	13.14	446 / 459
tonsil	0%	0	0 / 0	100%	14.06	45 / 45
ureter	0%	0	0 / 0	100%	2.99	1 / 1
adipose	98%	244.36	1180 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	14.40	28 / 29
spleen	95%	201.15	230 / 241	0%	0	0 / 0
thymus	77%	76.98	501 / 653	14%	1.45	86 / 605
muscle	63%	55.81	505 / 803	0%	0	0 / 0
peripheral blood	61%	529.59	571 / 929	0%	0	0 / 0
liver	19%	28.49	43 / 226	38%	2.01	155 / 406
pancreas	7%	3.80	24 / 328	48%	2.41	86 / 178
adrenal gland	37%	24.49	95 / 258	17%	0.86	38 / 230
brain	6%	3.51	158 / 2642	47%	3.34	330 / 705
blood vessel	33%	18.15	434 / 1335	0%	0	0 / 0
prostate	25%	15.06	61 / 245	8%	0.31	38 / 502
kidney	17%	19.36	15 / 89	11%	0.48	100 / 901
heart	11%	7.27	96 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	8%	0.19	6 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006974	Biological process	DNA damage response
GO_0008283	Biological process	cell population proliferation
GO_0006270	Biological process	DNA replication initiation
GO_0043596	Cellular component	nuclear replication fork
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0019899	Molecular function	enzyme binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0003697	Molecular function	single-stranded DNA binding
GO_0046872	Molecular function	metal ion binding
GO_0003688	Molecular function	DNA replication origin binding

Gene name	MCM10
Protein name	Protein MCM10 homolog (HsMCM10) Protein MCM10 homolog Minichromosome maintenance 10 replication initiation factor
Synonyms	PRO2249 hCG_40780
Description	FUNCTION: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 . .
Accessions	ENST00000378694.1 ENST00000479669.5 ENST00000378714.8 [Q7L590-2] C9J600 Q5T670 ENST00000484800.6 [Q7L590-1] Q7L590

MCM10 report