MC5R report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MC5R at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MC5R at tissue level.

III. Associated gene sets

GO_0019222Biological processregulation of metabolic process
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0042562Molecular functionhormone binding
GO_0004977Molecular functionmelanocortin receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMC5R
Protein nameMelanocortin receptor 5 (MC5-R) (MC-2)
Synonyms
DescriptionFUNCTION: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

AccessionsENST00000589410.2
P33032
ENST00000324750.5