I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| interneuron | 4 studies | 27% ± 13% | |
| GABAergic neuron | 4 studies | 27% ± 10% | |
| astrocyte | 4 studies | 20% ± 4% | |
| glutamatergic neuron | 4 studies | 33% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| interneuron | 4 studies | 27% ± 13% | |
| GABAergic neuron | 4 studies | 27% ± 10% | |
| astrocyte | 4 studies | 20% ± 4% | |
| glutamatergic neuron | 4 studies | 33% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 24% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 5750.15 | 258 / 258 | 99% | 27.68 | 228 / 230 |
| brain | 99% | 6173.38 | 2621 / 2642 | 100% | 41.58 | 703 / 705 |
| uterus | 100% | 5390.38 | 170 / 170 | 98% | 17.25 | 451 / 459 |
| prostate | 100% | 4408.17 | 245 / 245 | 97% | 12.47 | 485 / 502 |
| bladder | 100% | 3711.29 | 21 / 21 | 96% | 15.41 | 483 / 504 |
| esophagus | 100% | 3505.47 | 1442 / 1445 | 93% | 8.83 | 171 / 183 |
| kidney | 100% | 4168.30 | 89 / 89 | 92% | 17.71 | 830 / 901 |
| pancreas | 96% | 1533.12 | 315 / 328 | 95% | 13.82 | 169 / 178 |
| intestine | 100% | 2526.86 | 965 / 966 | 91% | 10.64 | 478 / 527 |
| thymus | 100% | 6150.05 | 653 / 653 | 90% | 11.32 | 545 / 605 |
| lung | 100% | 3398.39 | 576 / 578 | 90% | 11.65 | 1037 / 1155 |
| breast | 100% | 2752.09 | 459 / 459 | 88% | 8.79 | 981 / 1118 |
| stomach | 100% | 2698.39 | 358 / 359 | 86% | 8.61 | 247 / 286 |
| skin | 97% | 1632.21 | 1758 / 1809 | 83% | 9.11 | 393 / 472 |
| ovary | 100% | 8925.77 | 180 / 180 | 79% | 8.15 | 338 / 430 |
| liver | 89% | 1147.15 | 201 / 226 | 32% | 2.70 | 131 / 406 |
| spleen | 100% | 4056.24 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.49 | 1 / 1 |
| adipose | 100% | 2644.74 | 1198 / 1204 | 0% | 0 | 0 / 0 |
| heart | 95% | 1639.62 | 819 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 94% | 1658.35 | 1252 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 8.79 | 41 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 8.19 | 24 / 29 |
| eye | 0% | 0 | 0 / 0 | 63% | 6.14 | 50 / 80 |
| muscle | 37% | 360.24 | 297 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 22% | 476.10 | 201 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007420 | Biological process | brain development |
| GO_0006508 | Biological process | proteolysis |
| GO_0005874 | Cellular component | microtubule |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0106423 | Molecular function | tubulin-tyrosine carboxypeptidase |
| GO_0005515 | Molecular function | protein binding |
| GO_0004181 | Molecular function | metallocarboxypeptidase activity |
| Gene name | MATCAP1 |
| Protein name | Microtubule associated tyrosine carboxypeptidase 1 Microtubule-associated tyrosine carboxypeptidase 1 (EC 3.4.17.17) (Microtubule-associated tyrosine carboxypeptidase) |
| Synonyms | MATCAP KIAA0895L |
| Description | FUNCTION: Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function . Also able to remove the C-terminal phenylalanine residue of alpha-tubulin TUBA8 . Recognizes adjacent tubulin dimers along the same protofilament . . |
| Accessions | I3L230 ENST00000563902.2 [Q68EN5-1] ENST00000561621.5 [Q68EN5-2] Q68EN5 ENST00000568563.5 ENST00000290881.11 [Q68EN5-1] |
