MASP2 | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	5 studies	52% ± 20%	Explore

Name	Number of supported studies	Average coverage
liver	3 studies	26% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	10338.49	226 / 226	91%	101.63	368 / 406
brain	84%	289.20	2210 / 2642	84%	2.14	594 / 705
esophagus	93%	237.95	1340 / 1445	51%	1.19	93 / 183
thymus	97%	262.45	632 / 653	38%	0.67	228 / 605
breast	97%	316.04	447 / 459	36%	0.73	402 / 1118
ovary	98%	363.78	177 / 180	32%	0.62	137 / 430
stomach	97%	242.34	349 / 359	31%	0.63	90 / 286
skin	97%	361.89	1761 / 1809	28%	0.52	131 / 472
prostate	96%	223.61	234 / 245	26%	0.44	131 / 502
intestine	99%	360.57	957 / 966	22%	0.55	118 / 527
pancreas	97%	201.75	317 / 328	24%	0.45	43 / 178
lung	91%	245.32	527 / 578	30%	0.58	341 / 1155
uterus	98%	375.05	167 / 170	19%	0.30	86 / 459
kidney	79%	115.47	70 / 89	36%	0.79	321 / 901
adrenal gland	89%	154.97	230 / 258	22%	0.37	51 / 230
bladder	90%	262.48	19 / 21	17%	0.35	86 / 504
spleen	100%	302.02	241 / 241	0%	0	0 / 0
blood vessel	97%	255.15	1290 / 1335	0%	0	0 / 0
muscle	96%	178.93	774 / 803	0%	0	0 / 0
adipose	93%	224.42	1117 / 1204	0%	0	0 / 0
heart	72%	97.39	616 / 861	0%	0	0 / 0
peripheral blood	40%	74.42	374 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	17%	0.24	5 / 29
tonsil	0%	0	0 / 0	16%	0.26	7 / 45
eye	0%	0	0 / 0	10%	0.18	8 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006958	Biological process	complement activation, classical pathway
GO_0001867	Biological process	complement activation, lectin pathway
GO_0006508	Biological process	proteolysis
GO_0005615	Cellular component	extracellular space
GO_0070062	Cellular component	extracellular exosome
GO_0005576	Cellular component	extracellular region
GO_0001855	Molecular function	complement component C4b binding
GO_0008233	Molecular function	peptidase activity
GO_0048306	Molecular function	calcium-dependent protein binding
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding
GO_0004252	Molecular function	serine-type endopeptidase activity

Gene name	MASP2
Protein name	MBL associated serine protease 2 Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain]
Synonyms
Description	FUNCTION: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. .
Accessions	A0A8V8TPN9 O00187 ENST00000400898.3 [O00187-2] A0A8V8TQL6 ENST00000400897.8 [O00187-1] ENST00000700094.1 A0A8V8TQY3 A0A8V8TPN3 ENST00000700095.1 A0A8V8TPA2 A0A8V8TP45 A0A8V8TPU1 ENST00000700089.1 ENST00000700096.1 ENST00000700097.1 ENST00000699958.1 A0A8V8TQY5 ENST00000700092.1 ENST00000700088.1 ENST00000700090.1 A0A8V8TQL2 ENST00000700091.1 A0A8V8TPT6 ENST00000700093.1

MASP2 report