I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 6 studies | 23% ± 7% | |
| epithelial cell | 5 studies | 32% ± 12% | |
| goblet cell | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 6 studies | 23% ± 7% | |
| epithelial cell | 5 studies | 32% ± 12% | |
| goblet cell | 3 studies | 17% ± 1% |
Insufficient scRNA-seq data for expression of MARVELD2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 1124.31 | 226 / 226 | 98% | 20.58 | 399 / 406 |
| lung | 100% | 890.41 | 576 / 578 | 99% | 18.98 | 1139 / 1155 |
| pancreas | 100% | 982.46 | 328 / 328 | 97% | 16.55 | 172 / 178 |
| prostate | 97% | 540.03 | 237 / 245 | 100% | 24.89 | 500 / 502 |
| thymus | 100% | 1941.14 | 653 / 653 | 96% | 34.23 | 580 / 605 |
| stomach | 75% | 914.53 | 271 / 359 | 98% | 22.22 | 280 / 286 |
| kidney | 100% | 818.64 | 89 / 89 | 71% | 10.08 | 636 / 901 |
| breast | 60% | 278.44 | 277 / 459 | 98% | 25.37 | 1097 / 1118 |
| intestine | 50% | 548.15 | 482 / 966 | 99% | 22.81 | 521 / 527 |
| bladder | 48% | 302.67 | 10 / 21 | 96% | 17.29 | 482 / 504 |
| esophagus | 40% | 428.24 | 577 / 1445 | 98% | 21.12 | 179 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 17.12 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.55 | 1 / 1 |
| ovary | 1% | 1.59 | 2 / 180 | 96% | 11.95 | 413 / 430 |
| uterus | 8% | 29.46 | 14 / 170 | 88% | 15.03 | 404 / 459 |
| skin | 86% | 558.98 | 1558 / 1809 | 6% | 0.36 | 26 / 472 |
| brain | 30% | 53.28 | 792 / 2642 | 3% | 0.16 | 20 / 705 |
| peripheral blood | 17% | 44.77 | 156 / 929 | 0% | 0 | 0 / 0 |
| adrenal gland | 3% | 5.11 | 9 / 258 | 4% | 0.34 | 10 / 230 |
| heart | 6% | 8.43 | 48 / 861 | 0% | 0 | 0 / 0 |
| adipose | 4% | 7.60 | 53 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.16 | 3 / 80 |
| spleen | 1% | 2.50 | 3 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 1.85 | 14 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007605 | Biological process | sensory perception of sound |
| GO_0061028 | Biological process | establishment of endothelial barrier |
| GO_0070830 | Biological process | bicellular tight junction assembly |
| GO_0045216 | Biological process | cell-cell junction organization |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0043220 | Cellular component | Schmidt-Lanterman incisure |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0030054 | Cellular component | cell junction |
| GO_0070160 | Cellular component | tight junction |
| GO_0061689 | Cellular component | tricellular tight junction |
| GO_0033010 | Cellular component | paranodal junction |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MARVELD2 |
| Protein name | Alternative protein MARVELD2 MARVEL domain containing 2 (Tricellulin isoform c) MARVEL domain-containing protein 2 (Tricellulin) MARVEL domain containing 2 MARVEL domain-containing protein 2 |
| Synonyms | TRIC |
| Description | FUNCTION: Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti . . |
| Accessions | ENST00000622835.4 ENST00000647531.1 [Q8N4S9-3] ENST00000454295.6 [Q8N4S9-3] ENST00000515844.1 ENST00000413223.3 D6RA09 ENST00000614617.4 ENST00000436532.7 ENST00000645446.1 [Q8N4S9-1] Q8N4S9 ENST00000612528.1 A0A0G2JN00 L8EAP3 A1BQX2 D6RAH8 ENST00000611349.1 ENST00000611064.4 ENST00000512803.5 A0A0G2JN23 A0A0G2JQ38 ENST00000325631.10 [Q8N4S9-1] ENST00000622563.4 |
