MAPKBP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1900425Biological processnegative regulation of defense response to bacterium
GO_0043124Biological processnegative regulation of canonical NF-kappaB signal transduction
GO_0032717Biological processnegative regulation of interleukin-8 production
GO_0046330Biological processpositive regulation of JNK cascade
GO_0005730Cellular componentnucleolus
GO_0097431Cellular componentmitotic spindle pole
GO_0005654Cellular componentnucleoplasm
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMAPKBP1
Protein nameMitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1)
Alternative protein MAPKBP1
Mitogen-activated protein kinase binding protein 1
SynonymsJNKBP1
KIAA0596
DescriptionFUNCTION: Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response . Involved in JNK signaling pathway (By similarity). .

AccessionsENST00000627631.1
ENST00000514566.5 [O60336-2]
ENST00000457542.7 [O60336-6]
ENST00000512970.5
ENST00000456763.6 [O60336-1]
D6R9F7
D6RHX7
L8E7J2
O60336
D6RAI2
ENST00000510535.1
ENST00000505373.5