MAP1LC3C report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MAP1LC3C at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MAP1LC3C at tissue level.

III. Associated gene sets

GO_0032527Biological processprotein exit from endoplasmic reticulum
GO_0000045Biological processautophagosome assembly
GO_0016236Biological processmacroautophagy
GO_0035973Biological processaggrephagy
GO_0009267Biological processcellular response to starvation
GO_0000422Biological processautophagy of mitochondrion
GO_0097352Biological processautophagosome maturation
GO_0006995Biological processcellular response to nitrogen starvation
GO_0005874Cellular componentmicrotubule
GO_0031410Cellular componentcytoplasmic vesicle
GO_0012505Cellular componentendomembrane system
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0000421Cellular componentautophagosome membrane
GO_0005829Cellular componentcytosol
GO_0005776Cellular componentautophagosome
GO_0031090Cellular componentorganelle membrane
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0008429Molecular functionphosphatidylethanolamine binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMAP1LC3C
Protein nameMicrotubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)
Synonyms
DescriptionFUNCTION: Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2 . Recruits all ATG8 family members to infecting bacteria such as S.typhimurium . May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins . .

AccessionsENST00000357246.4
Q9BXW4