Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 13 studies | 34% ± 14% | |
| epithelial cell | 3 studies | 28% ± 4% | |
| GABAergic neuron | 3 studies | 21% ± 4% | |
| glutamatergic neuron | 3 studies | 40% ± 5% | |
| group 3 innate lymphoid cell | 3 studies | 21% ± 3% |
Insufficient scRNA-seq data for expression of LZTFL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 1439.38 | 180 / 180 | 100% | 16.81 | 430 / 430 |
| brain | 100% | 1370.35 | 2633 / 2642 | 100% | 13.86 | 703 / 705 |
| breast | 100% | 1226.32 | 459 / 459 | 99% | 17.93 | 1107 / 1118 |
| thymus | 100% | 1978.37 | 653 / 653 | 99% | 22.31 | 598 / 605 |
| pancreas | 100% | 759.08 | 327 / 328 | 99% | 9.72 | 176 / 178 |
| lung | 99% | 1146.88 | 575 / 578 | 99% | 9.66 | 1138 / 1155 |
| esophagus | 100% | 952.88 | 1445 / 1445 | 98% | 8.85 | 179 / 183 |
| prostate | 100% | 1022.72 | 245 / 245 | 96% | 8.03 | 483 / 502 |
| bladder | 100% | 1020.24 | 21 / 21 | 96% | 9.27 | 483 / 504 |
| kidney | 100% | 1189.16 | 89 / 89 | 95% | 11.41 | 860 / 901 |
| intestine | 100% | 1115.74 | 966 / 966 | 95% | 9.54 | 501 / 527 |
| stomach | 100% | 798.57 | 359 / 359 | 94% | 9.70 | 270 / 286 |
| uterus | 100% | 1643.25 | 170 / 170 | 94% | 9.68 | 432 / 459 |
| adrenal gland | 100% | 1050.66 | 258 / 258 | 93% | 8.04 | 214 / 230 |
| skin | 100% | 1061.65 | 1803 / 1809 | 88% | 9.06 | 415 / 472 |
| liver | 99% | 559.23 | 223 / 226 | 51% | 2.97 | 208 / 406 |
| spleen | 100% | 857.49 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 984.45 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 917.90 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 8.76 | 43 / 45 |
| heart | 91% | 490.80 | 782 / 861 | 0% | 0 | 0 / 0 |
| muscle | 78% | 281.34 | 626 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 66% | 4.08 | 19 / 29 |
| eye | 0% | 0 | 0 / 0 | 36% | 2.47 | 29 / 80 |
| peripheral blood | 34% | 132.78 | 316 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0030317 | Biological process | flagellated sperm motility |
| GO_1903568 | Biological process | negative regulation of protein localization to ciliary membrane |
| GO_1903565 | Biological process | negative regulation of protein localization to cilium |
| GO_0005929 | Cellular component | cilium |
| GO_0005829 | Cellular component | cytosol |
| GO_0002177 | Cellular component | manchette |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LZTFL1 |
| Protein name | Leucine zipper transcription factor-like protein 1 Leucine zipper transcription factor like 1 Alternative protein LZTFL1 |
| Synonyms | |
| Description | FUNCTION: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. . FUNCTION: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. . FUNCTION: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. . FUNCTION: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. . FUNCTION: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. . FUNCTION: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. . |
| Accessions | ENST00000445698.1 Q9NQ48 ENST00000539217.5 [Q9NQ48-3] A0A7P0TBA5 ENST00000684620.1 [Q9NQ48-2] C9J0R9 ENST00000472635.5 L8EB17 ENST00000418700.6 H7C488 A0A8V8TP88 ENST00000490463.6 F8VR53 ENST00000699187.1 A0A7P0TA24 ENST00000440576.2 ENST00000296135.11 [Q9NQ48-1] ENST00000492333.5 A0A7P0TAT3 |
