LYZL6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LYZL6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LYZL6 at tissue level.

III. Associated gene sets

GO_0031640Biological processkilling of cells of another organism
GO_0009566Biological processfertilization
GO_0007342Biological processfusion of sperm to egg plasma membrane involved in single fertilization
GO_0042742Biological processdefense response to bacterium
GO_0009986Cellular componentcell surface
GO_0097225Cellular componentsperm midpiece
GO_0097524Cellular componentsperm plasma membrane
GO_0001669Cellular componentacrosomal vesicle
GO_0036126Cellular componentsperm flagellum
GO_0005576Cellular componentextracellular region
GO_0003796Molecular functionlysozyme activity

IV. Literature review

[source]
Gene nameLYZL6
Protein nameLysozyme-like protein 6 (EC 3.2.1.17)
Epididymis secretory sperm binding protein Li 6a (Lysozyme B) (Lysozyme-like 6)
Lysozyme like 6 (Lysozyme-like protein 6)
SynonymsLYZB
UNQ754/PRO1485
LYC1
HEL-S-6a
hCG_32603
DescriptionFUNCTION: May be involved sperm-egg plasma membrane adhesion and fusion during fertilization . Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus . Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH . Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6 . .

AccessionsA0A080YUZ6
ENST00000618542.4
ENST00000617692.1
ENST00000632590.1
ENST00000615905.5
ENST00000612374.2
ENST00000633033.1
A0A087WXX7
O75951