LTO1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042273Biological processribosomal large subunit biogenesis
GO_0006413Biological processtranslational initiation
GO_0106035Biological processprotein maturation by [4Fe-4S] cluster transfer
GO_0000723Biological processtelomere maintenance
GO_0005575Cellular componentcellular_component
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLTO1
Protein nameLTO1 maturation factor of ABCE1 (Oral cancer overexpressed 1)
LTO1 maturation factor of ABCE1 (cDNA FLJ58145, highly similar to Oral cancer overexpressed protein 1)
LTO1 maturation factor of ABCE1
LTO1 maturation factor of ABCE1 (Oral cancer overexpressed protein 1-A)
Protein LTO1 homolog (Oral cancer-overexpressed protein 1) (Tumor-amplified and overexpressed sequence 1)
SynonymsTAOS1
ORAOV1
DescriptionFUNCTION: The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery . May be required for biogenesis of the large ribosomal subunit and initiation of translation . May play a role in the regulation of proline metabolism and ROS production . .

AccessionsENST00000535657.5
ENST00000536870.5
F5GZY6
ENST00000441922.6
F5GWS9
F5H179
F5H8D9
F5H6T8
A6YPU5
ENST00000542341.1
B4DFA5
Q8WV07
ENST00000538554.6
ENST00000539414.5
ENST00000537272.6
ENST00000535542.5
H3BPK6
ENST00000279147.9
ENST00000543562.1