I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 23% ± 7% | |
| glutamatergic neuron | 3 studies | 31% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 23% ± 7% | |
| glutamatergic neuron | 3 studies | 31% ± 8% |
Insufficient scRNA-seq data for expression of LSM11 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2057.79 | 1445 / 1445 | 100% | 5.15 | 183 / 183 |
| intestine | 100% | 1438.73 | 966 / 966 | 100% | 5.43 | 526 / 527 |
| prostate | 100% | 1386.39 | 245 / 245 | 100% | 5.37 | 501 / 502 |
| uterus | 100% | 1719.79 | 170 / 170 | 100% | 7.11 | 458 / 459 |
| breast | 100% | 623.58 | 458 / 459 | 100% | 5.77 | 1115 / 1118 |
| bladder | 100% | 3234.24 | 21 / 21 | 99% | 4.72 | 501 / 504 |
| ovary | 100% | 867.49 | 180 / 180 | 99% | 3.02 | 424 / 430 |
| lung | 99% | 605.46 | 574 / 578 | 99% | 3.80 | 1146 / 1155 |
| thymus | 99% | 433.28 | 646 / 653 | 99% | 3.29 | 598 / 605 |
| stomach | 99% | 639.81 | 356 / 359 | 99% | 5.17 | 282 / 286 |
| adrenal gland | 99% | 653.84 | 255 / 258 | 98% | 5.20 | 226 / 230 |
| skin | 100% | 568.59 | 1805 / 1809 | 96% | 5.18 | 454 / 472 |
| kidney | 97% | 359.88 | 86 / 89 | 96% | 4.35 | 868 / 901 |
| pancreas | 94% | 343.72 | 307 / 328 | 99% | 4.98 | 176 / 178 |
| brain | 92% | 1030.87 | 2424 / 2642 | 100% | 6.28 | 705 / 705 |
| liver | 72% | 196.25 | 163 / 226 | 91% | 2.73 | 368 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 5.55 | 29 / 29 |
| spleen | 100% | 537.41 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 4.98 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.89 | 1 / 1 |
| blood vessel | 100% | 757.72 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 99% | 596.92 | 1187 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 3.79 | 76 / 80 |
| heart | 73% | 214.25 | 625 / 861 | 0% | 0 | 0 / 0 |
| muscle | 71% | 212.34 | 572 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 32% | 179.12 | 295 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1900087 | Biological process | positive regulation of G1/S transition of mitotic cell cycle |
| GO_0006398 | Biological process | mRNA 3'-end processing by stem-loop binding and cleavage |
| GO_1902275 | Biological process | regulation of chromatin organization |
| GO_0005683 | Cellular component | U7 snRNP |
| GO_0071204 | Cellular component | histone pre-mRNA 3'end processing complex |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005697 | Cellular component | telomerase holoenzyme complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0071209 | Molecular function | U7 snRNA binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LSM11 |
| Protein name | U7 snRNA-associated Sm-like protein LSm11 Alternative protein LSM11 |
| Synonyms | |
| Description | FUNCTION: Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing . Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed . Required for cell cycle progression from G1 to S phases (By similarity). Binds specifically to the Sm-binding site of U7 snRNA . . |
| Accessions | ENST00000286307.6 L0R895 P83369 |
