LRRC52 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LRRC52 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LRRC52 at tissue level.

III. Associated gene sets

GO_1903818Biological processpositive regulation of voltage-gated potassium channel activity
GO_0022414Biological processreproductive process
GO_0051649Biological processestablishment of localization in cell
GO_0071805Biological processpotassium ion transmembrane transport
GO_0008076Cellular componentvoltage-gated potassium channel complex
GO_0005886Cellular componentplasma membrane
GO_0005249Molecular functionvoltage-gated potassium channel activity
GO_0099104Molecular functionpotassium channel activator activity
GO_0005515Molecular functionprotein binding
GO_0044325Molecular functiontransmembrane transporter binding

IV. Literature review

[source]
Gene nameLRRC52
Protein nameLeucine-rich repeat-containing protein 52 (BK channel auxiliary gamma subunit LRRC52)
Synonyms
DescriptionFUNCTION: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. KCNU1 channel auxiliary protein. May modulate KCNU1 gating properties. .

AccessionsQ8N7C0
ENST00000294818.2