LRRC14 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LRRC14 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LRRC14 at tissue level.

III. Associated gene sets

GO_0032088Biological processnegative regulation of NF-kappaB transcription factor activity
GO_0034122Biological processnegative regulation of toll-like receptor signaling pathway
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0019900Molecular functionkinase binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLRRC14
Protein nameLeucine-rich repeat-containing protein 14
Leucine rich repeat containing 14
SynonymsKIAA0014
DescriptionFUNCTION: Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB. .

AccessionsE9PP40
ENST00000525766.1
ENST00000529022.5
ENST00000292524.6
E9PNL0
Q15048
E9PRP5
ENST00000530854.1
ENST00000527730.1